Neutrophil-to-Lymphocyte Ratio (NLR) and its Correlation with Severity of Decompensated Liver Cirrhosis based on Child-Turcotte Pugh (CTP) Score
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 2
Abstract
ABSTRACT Introduction: Neutrophil-to-Lymphocyte Ratio or NLR is a ratio used as a marker for ongoing inflammation process and is independently related to poor clinical outcomes among liver cirrhosis patients. Aim: To determine any significant correlation between NLR and Child-Turcotte Pugh (CTP) score among decompensated liver cirrhosis patients in a tertiary referral centre in Medan, Indonesia. Materials and Methods: The cross-sectional study involved patients diagnosed with liver cirrhosis in Haji Adam Malik General Hospital, Medan, Indonesia between May 2016-May 2017. The study enrolled 54 cirrhotic patients, regardless of aetiologic agent. CTP score was fulfilled by using two methods, bilirubin, albumin, and INR was noted from medical record registry and the rest, ascites and encephalopathy, were assessed using physical examination and interview process on the same day of the patient admission. Spearman correlation test was performed to determine the correlation between two variables, while the demographic characteristic was presented in a single table with mean or median and standard deviation in it. Results: A significant correlation between NLR and CTP score was obtained (p=0.008) and it was positively correlated (r=0.326). Conclusion: Shifting use of CTP score to NLR ratio still needs further study to acknowledge its potential as mortality and prognosis predictor independently.
Authors and Affiliations
Taufik Sungkar, Muhammad Fakhrur Rozi, Leonardo Basa Dairi, Lukman Hakim Zain
Keywords
Related Articles
- EP ID EP559041
- DOI 10.7860/JCDR/2019/39895.12618
- Views 114
- Downloads 0
Knot of Henry: Role in Tendon Transfer
The term “Master knot of Henry” refers to the site of cross connections between long (extrinsic) tendons of foot namely Flexor Digitorum Longus Tendon (FDLT) and Flexor Hallucis Longus Tendon (FHLT). This chiasmatic stru...
Aortopulmonary Window: Case Report of Survival in Untreated Adult Patient
ABSTRACT Aortopulmonary window is a rare congenital communication between ascending aorta and main pulmonary artery. The condition carries poor prognosis in absence of early corrective surgery. Few case reports exist in...
Acute Kidney Injury: Prevalence and Outcomes in Southern Indian Population
ABSTRACT Introduction: Acute Kidney Injury (AKI) is characterised by a rapid reduction in the kidney function and gets effected to varying degrees based on the aetiology. An AKI increases the chances of Chronic Kidney Di...
Maternal Anaemia is a Risk Factor for Anaemia in Infants at 14-16 Weeks-Need for Early Initiation of Iron Supplementation
ABSTRACT Introduction: Exclusive Breast Feeding (EBF) is recommended uniformly for all infants till six months. It is believed that since bioavailability of iron in breastmilk is high this along with the fetal iron store...
Postpartum Depression in Women: A Risk Factor Analysis
Introduction: Postpartum Depression (PPD) is a known entity affecting not only the women but the whole family. It affects women more harshly and chronically due to their increased stress sensitivity, maladaptive coping s...