New insights into the pathophysiology of nonalcoholic fatty liver disease
Journal Title: Annals of Hepatology - Year 2009, Vol 8, Issue 1
Abstract
The consequences of pathologic adipose tissue accumulation have been described for almost all organs. Nonalcoholic fatty liver disease (NAFLD) is considered the most relevant hepatic manifestation of obesity. There is great interest in the study of NAFLD, and new insights into its pathogenic process have been described. Currently, in addition to insulin resistance, which was considered the hallmark of this disease, endocrine, immunologic, and central nervous system factors are attracting interest as explanatory variables. In this review, new factors associated with the main theories on the pathophysiology of NAFLD are analyzed.
Authors and Affiliations
Norberto Chávez-Tapia, Misael Uribe, Guadalupe Ponciano-Rodríguez, Roberto Medina-Santillán, Nahum Méndez-Sánchez
Keywords
Related Articles
- EP ID EP77838
- DOI -
- Views 138
- Downloads 0
Diagnosis of patients with suspected chronic hepatitis C infection
The current optimal approach to detecting hepatitis C virus (HCV) infection involves screening people for risk factors and only testing selected individuals at risk. Blood transfusion from infectious donors, unsafe thera...
Sirolimus may be associated with early recurrence of biliary obstruction in liver transplant patients undergoing endoscopic stenting of biliary strictures
Introduction. Recurrent biliary obstruction necessitating premature repeat endoscopic retrograde pancreatography (ERCP) remains a costly and morbid problem in patients undergoing treatment of post-orthotopic liver transp...
Primary care practitioners survey of non-alcoholic fatty liver disease
Background. The rising incidence of non alcoholic fatty liver disease (NAFLD) mirrors the epidemics of obesity and metabolic syndrome. Primary care practitioners (PCPs) are central to management of patients with NAFLD, b...
Chronic hepatitis C treatment in näive patients
Hepatitis C (HCV) is a major public health problem worldwide and it is considered that there are about 180 millions of infected people. The natural history of hepatitis C shows that, of those individuals affected by a pr...
Cholesterol cholelithiasis in pregnant women: pathogenesis, prevention and treatment
Epidemiological and clinical studies have found that gallstone prevalence is twice as high in women as in men at all ages in every population studied. Hormonal changes occurring during pregnancy put women at higher risk....