New Materials for Bone Regeneration
Journal Title: BULETINUL INSTITUTULUI POLITEHNIC DIN IASI, CHIMIE SI INGINERIE CHIMICA - Year 2018, Vol 64, Issue 4
Abstract
Tissue engineering applications are being developed with the aim to regenerate, remodel, replace or support damaged tissues and organs. Many types of biomaterials have been studied for this purpose. The need for development of new biomimetic materials was the answer for many researchers. Scaffolds utilized in diverse applications of medicine, particularly, for bone tissue engineering must include mechanical properties, integration with host, osteoinductive (actively induce bone formation), osteoconductive (guide and support bone regeneration) properties and material biocompatibility. Also they can act as three-dimensional vehicles to deliver cells.to the human body. The best selections for bone defect repair were considered autografts (from the patient) and allografts (from the donor). Wheter or not multiple complications and risks were connected to the use of both types of grafts (Logeart et al., 2005), these remain the principal options for the doctors and patients. Bone is always colonized by osteoblasts and osteoclast cells, so it must be considered as a living tissue.
Authors and Affiliations
MARIA SPIRIDON, GRAȚIELA PIRCALABIORU
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ABSTRACT OF PhD THESIS