New medicines and theirs adverse events in therapy of chronic HCV infection
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 10
Abstract
On beginning of years 90, recombined interferon use in therapy of patients with chronic HCV infection was effective at about 15%. Associating of this therapy from rybavirin, and then replacement recombined interferon by pegylated interferon improved antiviral of treatment effectiveness considerably.In this article were presented the researches on the efficiency and adverse effects of new interferons and nucleoside analogs in patients with HCV infection. In relation to the same group of the patients were discussed the latest results of the researches on the new antivirus preparations: inhibitors of protease or polymerase and cyclophilin inhibitors.Introduced investigations show, that multidirectional development of investigations over well-known and it will bring new antiviral medicines soon to best's tolerance of therapy, which will be she could be shorter guaranteing yet considerably higher antiviral effectiveness.
Authors and Affiliations
Tadeusz Łapiński, Robert Flisiak
Keywords
Related Articles
- EP ID EP53763
- DOI -
- Views 169
- Downloads 0
Severe macroangiopathic hemolytic anemia in a patient with coarctation of the aorta – presentation of a rare case and review of the literature
replacement, rarely it has been observed in other cases of the cardiovascular anomalies. In this paper we present a rare case of severe hemolytic anemia necessitating repeated blood transfusions in a 65-year old women wi...
Nonspecific interstitial pneumonia, organizing pneumonia and other rare interstitial pneumonias
Nospecific interstitial pneumonia (NSIP) is the second and organizing pneumonia (OP) is the third, after the idiopathic interstitial fibrosis, most common form of the idiopathic interstitial pneumonias. Except of idiopat...
Zastosowanie cytometrii przepływowej w diagnostyce neutropenii
Granulocyty wielojądrzaste, neutrofile, stanowią najważniejszy element komórkowy wrodzonej odpowiedzi immunologicznej. Powstają one w szpiku na drodze różnicowania z wielopotencjalnej komórki macierzystej. Kolejne stadia...
Skuteczność kinesiotapingu w leczeniu urazów tkanek miękkich u młodych sportowców
<b>Cel pracy. </b>Celem pracy była ocena skuteczności kinesiotapingu w leczeniu urazów tkanek miękkich u młodych zawodników piłki nożnej.<br><b>Materiał i metody.&a...
Polymorphism of C1q complement (rs292001) occurrence in systemic lupus erythematosus patients
<b>Introduction.</b> Systemic lupus erythematosus (SLE) is a chronic, autoimmunological disease. The cause of disease is still unknown. It may be assumed that genetic predisposition can predis...