New Phase in Gastric Carcinoma Diagnosis: Haematological Biomarkers As Screening Markers
Journal Title: New Indian Journal of Surgery - Year 2019, Vol 10, Issue 2
Abstract
Gastric carcinomas are a commonly encountered malignancy worldwide. In India though the incidence is low as compared to worldwide statistics, it accounts for significant morbidity and mortality. Prognosis remains poor even today due to delayed presentations and delay in diagnosing. In recent years, hematological parameters are being studied as prognostic indicators for various cancers. There are not many studies on these hematological biomarkers as screening parameters in Gastric cancers. So we conducted a retrospective single center study to evaluate if these blood biomarkers can be utilized as screening parameters for Gastric malignancies. Aims & objectives is to determine if blood parameters are significantly different in patients with Gastric malignancies as compared to control cases. Hundred (100) cases of gastric malignancy and equal number of control – age, gender matched to cases without malignancy or infection were included. Both groups, evaluated with routine complete blood count and upper GI endoscopy were included. Hematological parameters like hemoglobin, neutrophils and lymphocyte count, Platelet count (PC), mean platelet volume, MPV/PC ratio, Platelet/ MPV ratio, red blood cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR), Monocyte/Lymphocyte ratio, and “Hematological MAHE- N-K index” were calculated and compared to look for statistical differences. We observed Blood biomarkers are statistically different in Gastric malignancy patients in comparison to controls. So we conclude that Hematological biomarkers can be utilized as a screening markers in Gastric malignancy.
Authors and Affiliations
Naveen PG
Keywords
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- EP ID EP594301
- DOI 10.21088/nijs.0976.4747.10219.1
- Views 73
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