NIOSOMES- A NOVEL DRUG CARRIER FOR DRUG TARGETING
Journal Title: Mintage journal of pharmaceutical and medical sciences - Year 2016, Vol 5, Issue 2
Abstract
Abstract: Niosomes are vesicular drug delivery systems made of cholesterol and non ionic surfactants. Various novel drug delivery systems available for targeting of drugs include liposomes, nanoparticles, and resealed erythrocytes. Because of the instability and higher cost liposomes are less preferred over niosomes. The application of vesicular systems in cosmetics and for therapeutic purpose may offer several advantages for niosomes. They improve the therapeutic performance of the drug molecules by delayed clearance from the circulation, protecting the drug from biological environment and restricting effects to target cells. Niosomes have great drug delivery potential for targeted delivery of anti-cancer, anti-infective agents. Drug delivery potential of niosome can enhance by using novel concepts like proniosomes and aspasome. Niosomes also serve better aid in diagnostic imaging and as a vaccine adjuvant. Thus these areas need further exploration and research so as to bring out commercially available niosomal preparation. This article mainly focuses on the significance, advantages over other drug delivery systems, manufacturing methods, characterization methods, current research in niosomal drug delivery and their limitations.
Authors and Affiliations
a. krishna sailaja
Keywords
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