NUCLEAR AND INFRANUCLEAR LESIONS OF 3, 4, 6 CRANIAL NERVES AND THEIR CLINICORADIOLOGICAL CORRELATION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 94
Abstract
BACKGROUND Palsies of any of the three cranial nerves supplying the extraocular muscles have their own presentations, disturbing ocular motility. The aim is to study the demography and clinicoradiological manifestations of patients with nuclear and infranuclear lesions of 3, 4 and 6 cranial nerves. MATERIALS AND METHODS This was a descriptive study. We analysed nuclear and infranuclear lesions of 3, 4 and 6 cranial nerves of inpatients of Rajiv Gandhi Government General Hospital, Chennai after taking informed consent. X-ray skull, CT brain and MRI brain plain and contrast were done in all the patients, in the Department of Radiology in Rajiv Gandhi Government General Hospital, Chennai. Inclusion Criteria- Patients with Nuclear and infranuclear lesions of 3, 4 and 6 cranial nerves, who were inpatients in Rajiv Gandhi Government General Hospital, Chennai, between February 2011 to December 2013. Exclusion Criteria- Patients with lesions of 3, 4 and 6 cranial nerves following head trauma were excluded from this study. RESULTS Out of the 40 patients studied, 15 had isolated unilateral 3rd, three had 4th, one had unilateral 6th nerve palsy. 8 had combinations of cranial nerve palsy in the form of unilateral 3, 4, 6 nerves’ involvement. Bilateral cranial nerves, 3, 4 and 6 involvement found in 2 patients (Squamous cell carcinoma of the nasopharynx, and aspergilloma). 8 patients had bilateral 6th nerve palsy. 28 patients had abnormal MRI and 10 patients had abnormal CT findings. CONCLUSION Commonly affected was the 3rd, followed by 4th, and 6th cranial nerve. Bilateral 6th and unilateral 3, 4, 6 were the commonest presentations, followed by bilateral 3, 4, 6 cranial nerves’ involvement. MRI was abnormal in 70% of the patients, whereas CT was abnormal only in 25% of patients. The commonest cause was Diabetes Mellitus, even in imaging negative patients.
Authors and Affiliations
Viveka Saravanan R, Thamil Pavai N, Lakshmi Narasimhan R
Keywords
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- EP ID EP279844
- DOI 10.14260/jemds/2017/1472
- Views 77
- Downloads 0
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