Obesity and Clozapine Use in Schizophrenia
Journal Title: Obesity Research - Open Journal - Year 2016, Vol 3, Issue 2
Abstract
Introduction: Schizophrenia is a chronic mental disorder, and treatment is based on the use of antipsychotics, such as clozapine. These drugs have been associated with obesity and metabolic changes. Objective: A systematic review to assess the association of obesity with the use of clozapine in schizophrenic patients. Method: It was made a search for articles in PUBMED and Capes of the regular databases with the keywords “Schizophrenia” “obesity” “clozapine” “weight gain”. The search included articles in English that were published between 2004 and 2015. We included only articles with retrospective studies and the following inclusion criteria: both sexes, patients older than 20 years, use of time of clozapine minimum of three months and sample size less than 50 individuals. Results: They were selected 4 articles contemplated the inclusion criteria. In all items selected for this study, obesity was associated with clozapine. Conclusions: There is a higher prevalence of overweight and obesity in patients with schizophrenia compared with the general population, this is due to some factors such as the use of atypical antipsychotics, such as clozapine.
Authors and Affiliations
Karine Zortea
Keywords
Related Articles
- EP ID EP554217
- DOI 10.17140/OROJ-3-124
- Views 171
- Downloads 0
Physical Education Teacher Education: The Key to Eliminating Childhood Obesity
Physical Education Teacher Education (PETE) will be the key to eliminating childhood obesity for the future by preparing physical education teacher candidates in the knowledge and skills they need to teach P-12 students,...
Challenges of Healthy Eating Habits in Rural Communities
The purpose of this study is to utilize multiple case study to investigate the challenges of healthy eating habits in rural communities in Arkansas, and to identify the differences between these communities (Community A...
Adipocytokines: A Potential Link Between Obesity and CNS Disorders
The interrelationships between obesity and high fat mass with different chronic pathophysiological conditions have been taken into consideration in recent decades along with the growing prevalence of obesity. Epidemiolog...
Daily Calcium Intervention for a Weight-Loss Program Resulted in More Significant Decreases in Body Weight, BMI, Body Fat Mass, and Body Fat Percentage
The purpose of this study was to assess of calcium intervention on the effectiveness of a weight-loss program for obese people. All subjects had an initial BMI (body mass index) >24 kg/m2 and low calcium diet (<500 mg/d...
Supplementation with Mix of Garcinia cambogia Extract, Yerba Mate Extract, and Guarana Extract Lowers Body Fat but has no Effects on High-Density Lipoprotein Cholesterol Level
Background Obesity and being overweight have become modern health problems due to energy intake being higher than expenditure. The obesity epidemic refers to the worldwide increase in excess weight according to the World...