Ocular complications in thalassemia major patients treated with deferoxamine: a hospital-based, cross-sectional study
Journal Title: Health Science Monitor - Year 2024, Vol 3, Issue 4
Abstract
Background & Aims: β-thalassemia is a severe hereditary disorder caused by defective globin synthesis. Patients suffering from β-thalassemia major require regular blood transfusion therapy to survive. Sight-threatening ocular abnormalities are quite common among these patients. This study was planned to evaluate the prevalence of ocular complications in multi-transfused patients with β-thalassemia who have been receiving deferoxamine. Materials & Methods: Thirty thalassemic patients receiving deferoxamine were studied in this cross-sectional descriptive study. All eligible subjects underwent an ophthalmologic examination, including the Humphrey visual field test, measurement of central corneal thickness (CCT), best-corrected visual acuity (BCVA), and central macular thickness (CMT). Results: Visual field defects were the most prevalent ocular abnormalities, observed in 50% of the studied subjects. Other ocular changes were as follows: bilateral cortical cataract (10%), macular pigmentary stippling (6.7%), punctate cortical opacity (3.3%), nuclear sclerosis cataract (3.3%), and macular pigmentary mottling (3.3%). Conclusion: The occurrence of ocular problems is common among thalassemic patients which necessitates long-term follow-up and regular ophthalmologic examination for these patients.
Authors and Affiliations
Naser Samadi Aidenloo,Qader Motarjemizadeh,Sina Hasani Shayan,
Keywords
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- EP ID EP764014
- DOI http://dx.doi.org/10.61186/hsm.3.4.292
- Views 11
- Downloads 0
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