Ocular fundus manifestations and the clinical application of fundal examinations in patients with chronic liver disease: a systematic review

Journal Title: Eye Science (Yanke Xuebao) - Year 2024, Vol 39, Issue 12

Abstract

Chronic Liver Disease (CLD) is a collective term for diseases resulting from the long-term effects of one or more damaging factors on the liver. It has a broad impact and affects a large patient population. Viral hepatitis, non-alcoholic fatty liver disease, and end-stage liver disease can involve the ocular fundus, leading to retinal exudates and hemorrhages. Additionally, structural changes in the fundus, such as the thickness of the choroid and different retinal layers, are associated with the severity of chronic liver disease. Through fundus examinations in patients with chronic liver disease, not only can ocular complications related to liver disease be prevented and treated, but these examinations may also offer potential value in the clinical assessment and monitoring of liver disease. This article reviews the potential ocular fundus abnormalities in patients with chronic liver disease under different etiologies, severities, and drug treatments. It discusses the progress in the clinical application of fundus structure and function examinations in patients with chronic liver disease. It compares the characteristics and appropriate clinical scenarios of various fundus examination methods in these patients and suggests potential new directions for the future use of fundus examinations in chronic liver disease management.

Authors and Affiliations

Zizheng CAO, Xiaohang WU, Liqiang ZHAN, Yuxian WU, Anqi YAN, Songming LI, Zhiyong GUO, Haotian LIN

Keywords

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  • EP ID EP761500
  • DOI 10.12419/24073101
  • Views 21
  • Downloads 0

How To Cite

Zizheng CAO, Xiaohang WU, Liqiang ZHAN, Yuxian WU, Anqi YAN, Songming LI, Zhiyong GUO, Haotian LIN (2024). Ocular fundus manifestations and the clinical application of fundal examinations in patients with chronic liver disease: a systematic review. Eye Science (Yanke Xuebao), 39(12), -. https://europub.co.uk./articles/-A-761500