Optimization of Water Based-extraction Methods for the Preparation of Bioactive-rich Ginger Extract Using Response Surface Methodology
Journal Title: European Journal of Medicinal Plants - Year 2014, Vol 4, Issue 8
Abstract
Aims: Evaluation of three extraction methods to prepare bioactive-rich ginger extract for incorporation into a functional beverage. Study Design: Response surface methodology. Methodology: For the preparation of bioactive-rich ginger extract with water, conventional hot water extraction, ultrasonic-assisted extraction and high pressure homogenization-assisted extraction were evaluated. Response surface methodology was employed to optimize the extraction conditions of each method with respect to the highest polyphenols, antioxidant capacity (ferric reducing antioxidant power; FRAP) and percent inhibition of low density lipoprotein (LDL) cholesterol oxidation. Results: Multiple response optimizations revealed that the optimum extraction conditions for each extraction method were 60min extraction time under 55°C for hot water extraction, 15min ultrasonication under 52°C for ultrasonic-assisted extraction and 62°C under 140MPa homogenization pressure for high pressure homogenization-assisted extraction. Conclusion: The extract prepared from the ultrasonic-assisted extraction method exhibited the highest polyphenol recovery and antioxidant activity, compared to the extracts prepared from other two methods.
Authors and Affiliations
K. D. P. P. Gunathilake, H. P. Vasantha Rupasinghe
Keywords
Related Articles
- EP ID EP350016
- DOI 10.9734/EJMP/2014/10322
- Views 130
- Downloads 0
In vitro Anti-inflammatory Evaluation of African Nutmeg (Monodora myristica) Seeds
Aim: To determine the anti-inflammatory potential of flavonoid rich fraction of Monodora myristica seeds. Study Design: In vitro evaluation of anti-inflammatory assays: Membrane stability, Inhibition of denaturation of a...
Carica papaya Latex Accelerates Wound Healing in Diabetic Wistar Rats
Aim: The wound healing ability of Carica papaya latex in excisional wound of alloxan induced diabetic wistar rats was investigated. Methodology: The excisional wounds of 24 diabetic rats in four equal groups were dressed...
A Review on Iranian Carum copticum (L.): Composition and Biological Activities
Aims: This paper examined thoroughly chemical composition and biological properties of Carum copticum. Study Design: Introduction on curtain characteristic of medicinal Ajowan (Carum copticum (L.)). Place and Duration...
Spasmolytic Action of Centaurium erythraea on Rabbit Jejunum is through Calcium Channel Blockade and NO Release
Objective: The aim of the present study was to assess the antispasmodic effect of the aqueous extract from aerial parts of Centaurium erythraea (AECE) on isolated rabbit jejunum. Methods: Myorelaxant and spasmolytic eff...
Antibacterial Activity of the Bioactive Fractions of Cyathula uncinulata (Amaranthaceae)
Cyathula uncinulata (Schrad.) Schinz is used in ethnomedicine in various parts of the world. This study isolated and characterized a bioactive compound from C. uncinulata based on its antibacterial activities. Separation...