Osteoporosis in Male Ankylosing Spondylitis Patients
Journal Title: International Journal of Bone and Rheumatology Research (IJBRR) - Year 2016, Vol 3, Issue 6
Abstract
The present study shows not only early bone loss in AS patients with active disease, but also a significant relationship between the inflammation markers as ESR and bone loss. These results clearly support the theory that the inflammatory process plays a pivotal role in the pathophysiology of osteoporosis in AS. Bone loss of vertebral mass occurs early in the course of AS. On the other hand lumbar spine bone densitometry is less sensitive for patients with long-standing AS, due to the false-negative results causedby syndesmophytes. Proximal femur is less affected by diseaserelated new bone formation. Therefore, it should be better used to evaluate bone mass in AS patients with long-standing disease. So bone loss occurs early in the disease and its progression is better assessed by using DXA at the femu
Authors and Affiliations
Eiman Soliman
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