Osteosarcoma: Current treatment trends and outcome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Osteosarcoma is more common in pediatric patients and in males In the US. there is ethic variation more common in individuals of black than white. Frequent causes includes: familial cases, bone dysplasia,fraumeni syndrome, and Rothmund Thomson syndrome. The role of water fluoridation is unclear. Diagnosis begins with X–ray,CT scan, PET scan, and bone scan, MRI, and biopsy. The biopsy of suspected osteosarcoma outside the facial region should be performed by an orthopedic oncologist. Conventional therapy is a combination of limb-salvage orthopedic surgery when possible (or amputation in some cases) and combination of high dose methotrexeate with other drugs added. In stage three osteosarcoma with lung metastases depends on the resectability of the primary tumor and lung nodules, degree of necrosis of the primary tumor, and number of metastases. Overall prognosis is about 30%.Osteosarcoma is the common bone tumor in dogs especially in aged large giant breed dogs.CT guided radiofrequency ablation and thermal ablation techniques are frequently used in bone tumor. Sarcomas are quite rare in the US, and are usually treated surgically, radiotherapy and chemotherapy.the US and the UK July is the sarcoma awareness month
Authors and Affiliations
Murtaza Mustafa, HM. Iftikhar, EM. IIIzam, MK. Nang, AM. Sharifa
Keywords
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- EP ID EP409166
- DOI 10.9790/0853-1711023238.
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