Osteosarcoma of the Mandible: Case Report And Review Of Literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Osteosarcomas are malignant neoplasms arising from mesenchymal stem cells or their early progenitor cells.The incidence of osteosarcoma is low in malignant tumors; however it is the most common primary tumor of bone.Conventional osteosarcoma has been classified depending on the predominant type of extracellular matrix into subtypes - osteoblastic, chondroblastic, fibroblastic.Osteosarcomas of the jaws have a similar male and female pedilection. Mandibular lesions are more frequent than those in the maxilla. The radiographic appearance of Osteosarcoma depends on the proportions between bone destruction, calcification, new bone production and periosteal new bone formation. Tissue biopsy is needed for a definitive diagnosis. The specimen should be taken from the center of the lesion to avoid including reactive periosteal bone in the specimen.Surgery is the primary treatment for Osteosarcoma of jaws but it cannot be depended as the sole treatment modality.Chemotherapy (CT) has become an important therapeutic adjuvant in the treatment of osteosarcomas of all sites. Here we present a case of Fibroblastic Osteosarcoma of the Mandible with a review of Literature.
Authors and Affiliations
Dr. Pushan Maity, Dr. Amit Ray, Dr. Monika Gupta
Keywords
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- EP ID EP369608
- DOI 10.9790/0853-1703093441
- Views 63
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