Outcome of Locally Delivered Antibiotics via Bone Cement in Infective Nonunion, Chronic Osteomyelitis and Joint infections, A Case Series
Journal Title: Journal of Pakistan Orthopaedic Association - Year 2018, Vol 30, Issue 02
Abstract
Objective: To determine the outcome of locally delivered antibiotics via bone cements in infective non-union, chronic osteomyelitis and joint infections Methods: The study was conducted between January 2016 to June 2017. Patient with chronic osteomyelitis and infective non-union of long bones were chosen. Debribement / sequestrectomy and antibiotics beads placement was done in chronic osteomyelitis. In selected cases antibiotic, coated nail was put and in arthroplasties, antibiotic was added to spacer as prophylaxis to infection. The infected bone was scraped out leaving an opening in the bone. The antibiotic beads were then packed into the opening and the wound was closed for 4-5 weeks when they were removed. Bone was fixed in case of instability, when there were no signs of infections per operatively. Results: Twenty-seven (90%) out of 30 patients showed no signs of recurrence of osteomyelitis at the mean of 15 months follow up. Infection subsided in 2 out of remaining 3 patients, with re- debridement and beads and 1 patient did not show any sign of improvement even after second procedure. No significant complication was noted during the study. Conclusion: Antibiotics loaded Beads in the treatment of chronic osteomyelitis are safe and effective. Its advantages include lower cost, low systemic effects of the drug, shorter hospital stay and high concentrations of antibiotics at the site of infection.
Authors and Affiliations
Muhammad Shoaib Khan, Imran Ali, AbidAli,Rashid Khan,Hidayatullah,Khabeer Ahmad Khattak,Muhammmad Afrasiyab
Keywords
Related Articles
- EP ID EP741701
- DOI -
- Views 49
- Downloads 0
One Stage Sequential Bilateral Total Knee Arthroplasty. Is it Safe?
Objective: Present study analyzed retrospectively the complications associated with one stage sequential bilateral Total Knee Arthroplasty. Methods: A total of 107 bilateral knee osteoarthritis (OA) patients who under...
Management of Femoral Bone Defect after Gunshot Injury using Circular External Fixator
Objectives: Retrospective evaluation of healing index (HI) and consolidation time (CT) of gunshot femoral bone loss managed using conventional Ilizarov frame (CIF) versus Talyar Spatial Frame (TSF) fixator. Methods: T...
Clinical Outcomes and Sturctural Integrity of Rotor Cuff Tears after Arthroscopic Single Row Repair
Aim: To determine the functional and structural outcomes of rotator cuff tears after arthroscopic single row repair with biodegradable suture anchors. Methods: This descriptive study was conducted in Hand & Upper Limb...
Is Medial Approach better than posterior approach for open Reduction & Internal Fixation of Supracondylar Fractures of Humerus in Children?
Objectives: The aim of this study is to find that whether the medial surgical approach is beneficial to patients in term of radiological and functional outcome as compared to posterior approach for open reduction & inter...
Functional Outcome in Triceps Muscle Sparing Versus Muscle Splitting Approach in Pediatric Supracondylar Humerus Fracture
Objective: To determine the functional outcome of posterior triceps muscle sparing versus muscle splitting approach in supracondylar humerus fracture in children. Methods: This prospective randomized controlled study...