Outcomes of accelerated corneal collagen cross-linking in keratoconus
Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 3
Abstract
Keratoconus (KC) is a degenerative noninflammatory disease of the cornea which is characterized be structural changes in the cornea which leads to progressive thinning and bulging in the central and/or peripheral part of the cornea and is accompanied by irregular astigmatism and significant vision impairment. Today, keratoconus treatment is focused on a stage of disease development. At progressive KC stages (II-III), corneal collagen cross-linking is performed. At the present, a latest-generation unit (UV-X™2000, Avedro) is used to perform accelerated cross-linking, which allows for a threefold decrease of the procedure duration (to 10 minutes) compared to the standard protocol Material and Methods. Corneal collagen cross-linking was performed in 71 patients (100 eyes). Results. Accelerated corneal collagen cross-linking for keratoconus stages II-III made it possible to stabilize the pathological process in 100% of cases, based on 12 month follow-up. Keratoconus stabilization was accompanied by: a decrease of astigmatism by 1.4 D and of the corneal refractive power by 3.2D; an increase of the corneal thickness by 8.8 nm; an increase of UCVA and BCVA in 96.5% and 89.6% of cases, respectively; and recovery of normal corneal architectonics according to confocal biomicroscopy data. Subjectively, 64 patients (90%) noted the improvement in the vision quality and better tolerance to spectacles correction.
Authors and Affiliations
G. Drozhzhyna, L. Troychenko, V. A. Naumenko, O. Ivanova, E. Sereda
On selenium deficiency in Graves’ disease patients with autoimmune ophthalmopathy
Background: The role of selenium (Se) deficiency in the development of thyroid associated ophthalmopathy has been actively debated in the literature. The question is still debated in Ukraine due to the absence of data bo...
Current surgical rehabilitation techniques for patients with total bilateral symblepharon
Purpose: To investigate the efficacy of a three-stage surgical rehabilitation technique for patients with bilateral total symblepharon; the technique has been developed and advanced and is being used at present at the Oc...
Experimental study of efficacy of intralamellar keratoplasty with corneal stromal substitute developed from decellularized porcine cornea
Backrgound: Enhancing methods for decellularization of animal corneas for the development of bioengineered corneal models with the following keratoplasty makes it possible to overcome the shortage of human donor material...
Improving the technique for controlled cryogenic destruction of conjunctival tumors located in the projection of the ciliary body onto the sclera: a preliminary report
Background: In case of controlled cryogenic destruction of an epibulbar tumor, making direct temperature measurements in the tumor and surrounding tissues during the treatment process is difficult and dangerous. Infrared...
Pre-treatment and post-treatment visual functions in congenital myopia alone versus congenital myopia complicated by amblyopia
Background: Congenital myopia is a particular form of refractive error which develops prenatally. The reported incidence of myopia in newborns has varied widely, ranging from 6–15% to 25–50%. In the vast majority of case...