OUTCOMES OF FOLLICULAR FLUSHING VERSUS NONFLUSHING ASPIRATION IN POOR OVARIAN RESPONDERS WOMEN UNDERGOING INTRACYTOPLASMIC SPER INJECTION - EMBRYO TRANSFER: A RANDOMIZED CLINICAL TRIAL.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 12
Abstract
Aim: The main objective of this trial was to compare three - times follicular flushing aspiration (FFA) during ovum pick up (OPU) via modified single lumen needle (MSLN) to conventional direct non -flushing follicular aspiration (NFA) via single lumen needle (SLN) regards number of retrieved cumulus-oocyte complex (COCs), as well as other outcomes of assisted reproductive technology ? embryo transfer cycles (ARF-ET) in women, had poor ovarian response (POR) after controlled ovarian hyperstimulation (COH). Patients and Methods: This prospective, randomized, concealed allocation, double-blinded, controlled, superiority trial was performed at Hawa specialized IVF center, Benha, El- Qulobia, Egypt, between May 2017 and September 2018. One hundred women with POR after COH undergoing ART ? ET cycles were allocated to OPU via MSLN/FFA (interventional group) or SLN/NFA (control group). Outcomes were number of retrieved COCs, Metaphase II (MII) oocytes, oocyte recovery rate (ORR), as well as outcomes of intracytoplasmic sperm injection (ICSI) procedures including fertilization rate (FR), implantation rate (IR), total cleavage embryo (ICE), number of women with positive B-HCG, clinical and ongoing pregnancy rate (CPR) (OPR) and live birth rate (LBR) per cycle as well as per ET. Results: The outcomes in both interventional as well as control groups was similar with no statistical significant differences regards number of retrieved oocytes (2.81 1.36 vs 2.62 1.82, p = 0.48), FR (68.36 12.36 vs 70.38 15.37, p = 0.47), IR (25.62 9.36 vs 24.82 10.36, p = 0.68), TCE (2.26 1.28 vs 2.36 1.36, p = 0.70), positive B-HCG (36% vs 38%, p = 0.83), CPR/ cycle (22% vs 20%, p = 0.80) and LBR / cycle (16% vs 14%, p = 6.78). While both groups were significantly differs in procedures time (7.81 3.61 vs 14.61 8.61, p < 0.0001) as well as total anaesthesia time (10.21 4.61 vs 16.81 8.72, p = 0.001). Conclusion: In women with POR undergoing ART ? ET cycles after COH, follicular flushing OPU is time-consuming despite similar outcomes including the number of retrieved mature oocytes to live birth rate.
Authors and Affiliations
Mohamed Anwar Elnory.
Keywords
Related Articles
- EP ID EP435304
- DOI 10.21474/IJAR01/8118
- Views 96
- Downloads 0
MODIFIED GROPERS APPLIANCE FOR ENHANCED ESTHETICS : A CASE THEME.
One of the dentist?s greatest restorative challenges is the esthetic rehabilitation of a young toddler who has suffered multiple tooth loss subsequent to rampant early childhood caries or extensive dental trauma. An ante...
EXERGETIC ANALYSIS OF A SOLAR ABSORPTION MACHINE.
Absorption refrigeration machines need energy for their proper functioning. Much of this energy is lost due to energy dissipation by friction or during heat transfer under temperature difference. But thanks to the variou...
THE PREVALENCE OF SMOKING HABITS, EXPOSURE, ATTITUDES, BEHAVIOR AND CURRICULUM TRAINING AMONG THE HEALTHCARE PROFESSION STUDENTS - A CROSS-SECTIONAL STUDY
Background: Healthcare providers have been the major focus for smoking cessation as well as they are in ideal position to educate and advice patients about the negative impact of smoking and serve as behavioural models f...
AUTOLOGOUS SERUM INJECTION IN CHRONIC URTICARIAL.
Background: Chronic urticaria is usually diagnosed when wheals occur daily or almost daily associated with redness and itching for more than 42 days due to leak of fluid from blood vessels in the dermis, however, these s...
CORRELATION BETWEEN THE EDIBLE FRESHWATER BIVALVES AND SOME ECOLOGICAL FACTORS AT SELECTED SITES OF CAGAYAN RIVER.
The edible freshwater bivalves identified in Cagayan River were: Batissa childreni, Corbicula manilensis and Psammotaea virescens. Corbicula manilensis was the most abundant species collected. High density and bigger siz...