Palliative Radiotherapy for Spinal Extramedullary Hematopoiesis in Thalassemia Major
Journal Title: International Blood Research & Reviews - Year 2015, Vol 3, Issue 3
Abstract
Introduction: Non-hepatosplenic Extramedullary Hematopoiesis (NHEMH) is seen as a compensation mechanism in the patients with hematologic dysfunction. Thalassemia is an autosomal recessive hematologic disorder. The tissue involvement is seen very rarely in thalasemia major. Case: A 45-years old patient diagnosed with thalassemia major was presented in this case report. The patient had splenectomy after 12 years from diagnosis and he was followed with continuous blood transfusions. Due to the newly emerged chest pain and dyspnea, he was evaluated with computed tomography. The operation was done for paraspinal masses caused by NHEMH. But same complaints were seen after 5 years from the operation. Paraspinal and sacral recurrences were detected in screening examinations. External palliative radiotherapy (ERT) was given to the patient with 3000 cGy total doses. Both clinical and radiological response was obtained with ERT. Conclusion: Radiotherapy might be considered as an efficient palliative treatment option for the thalassemia major patients with NHEMH masses recurring after operation.
Authors and Affiliations
Cigdem Usul Afsar, Feryal Karaca, Fatma Sert, SebnemIzmir Guner, Vehbi Ercolak, Erkut Erkurt, Candas Tunali
Keywords
Related Articles
- EP ID EP242464
- DOI 10.9734/IBRR/2015/17235
- Views 113
- Downloads 0
Effect of Momordica charantia (Bitter Melon) Leaves on Haemoglobin Concentration in Male Albino Rats
This research work was carried out to investigate the effect of the aqueous extract of Momordica charantia on haemoglobin concentration in albino rats. The aqueous extract of Momordica charantia was prepared from the lea...
Prevalence of Clinically Significant Alloantibodies among Transfusion Requiring Patients in a Tertiary Hospital in Sokoto, Nigeria
Aim: No data are available regarding the frequencies of clinically significant alloantibodies among patients requiring transfusion in Sokoto North western Nigeria. We intend to provide information on the prevalence of cl...
Occult Hepatitis B Virus Infection among Blood Donors; North Middle Libya
Background: Post transfusion hepatitis B (PTHB) continues to be an important public health concern in regard to blood transfusion in Libya. The inclusion of tests specifically for the hepatitis B surface antigen (HBsAg)...
Transfusion Transmissible Infections among Blood Donors at the Blood Bank of Medical College of Gwalior: A 5 Year Study
Introduction: Transfusion Transmitted Infections (TTIs) are a major problem associated with blood transfusion. Accurate estimates of risk of TTIs are essential for monitoring the safety of blood supply and evaluating the...
Assessment of CD4 Count and Some Haematological Parameters of HIV Positive Patients Co-infected with Hepatitis B Virus in Osun State, Nigeria
Background: Increased morbidity and mortality rates have been reported among patients co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV). Aims: To determine the prevalence of HBV infection am...