Pancreatic Cancer: Pathobiology, Treatment Options, and Drug Delivery
Journal Title: The AAPS Journal - Year 2010, Vol 12, Issue 2
Abstract
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the USA. The high mortality rate is partly due to lack of effective treatments. This review summarizes the pathobiology and current treatment options for pancreatic cancer. Moreover, the review discusses the opportunities of developing novel therapies for pancreatic cancer provided by the progress in understanding the genetic mutations, tumor microenvironment, cancer stem cells, and drug delivery.
Authors and Affiliations
Jing Li, M. Guillaume Wientjes, Jessie L. -S. Au
Keywords
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- EP ID EP681379
- DOI 10.1208/s12248-010-9181-5
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