PAP SMEAR And Its Histopathological Correlation For Early Detection Of Carcinoma Of Cervix
Journal Title: National Journal of Medical and Dental Research - Year 2018, Vol 6, Issue 3
Abstract
Vaginal cytology is a practical method for early detection of dysplasia and malignancy and therefore it should be established as a routine diagnostic aid in the Gynaecological outpatient department. The value of cytology smear is undisputed today. The facilities for cytology being limited in our country, it should be used for screening high risk groups rather than for mass screening. This study aimed to know the incidence of carcinoma cervix in and around Chhindwara, to reduce the morbidity and mortality due to carcinoma cervix by early diagnosis and treatment in the precancerous stage and to evaluate the efficiency of cytology by its correlation with Histopathology. MATERIAL & METHOD: This is a prospective study performed in the District Hospital Chhindwara for a period of three years from 2015-2017. The study group comprises of women >25 years of age attending the Gynaecological Out Patient Department with various complaints. After taking detailed clinical history Pap smears were collected by Ayre’s Spatula which were stained by Papanicolaou stain at pathology Laboratory and reported according to the Bethesda System. Lastly all suspicious smears were correlated by Histopathology. RESULTS: Out of 500 smears 25 smears were found to be abnormal. Sensitivity of Pap Smear was 61.5 % and Specificity was 96.5%.Incidence of Low grade Squamous Intraepithelial Lesion(LSIL) was 3.4 % , High grade Squamous Intraepithelial Lesion (HSIL) was 1.6 %, and Squamous Cell Carcinoma(SCC) 0.4%.There were 25 cases of dysplasia (LSIL+HSIL) out of which 22 were proved to be correlated by biopsy. 2 cases of frank malignancy were also proved to be moderately differentiated epidermoid carcinoma by Histopathology. There is 100% correlation in cases of frank malignancy. Overall correlation of Cytology with Histopathology was 88.8%.CONCLUSION: Vaginal cytology is a practical method for early detection of dysplasia and malignancy and therefore it should be established as a routine diagnostic aid in the Gynecological outpatient department.
Authors and Affiliations
Ranjana Tandekar, Sanjay Totade, R Tandekar, S Moitra
Keywords
Related Articles
- EP ID EP571957
- DOI -
- Views 131
- Downloads 0
Diagnosis And Management Of Submandibular Duct Sialoliths: Report Of 2 Cases
Sialolithiasis refers to the formation of calcareous concentration or sialoliths in the salivary duct leading to obstruction of the salivary flow, resulting in salivary ectasia, sometimes even dialation of the salivary...
Study The Association Between Microalbuminuria And In hospital Complications Of Acute St Segment Elevation Myocardial Infarction (STEMI ) In Nondiabetic Patients
Background: Microalbuminuria occurs in diabetic patients with acute myocardial infarction but it has been reported that microalbuminuria occurs in non diabetic patients with acute myocardial infarctio...
A Study To Find Out The Dermatological Manifestations In Patients Of Diabetes Mellitus
As all of us know that diabetes affects multisy-stems of the human body, as Skin is the largest organ of the body so more are the complications, aim of this study was to find out the Dermatologycal manifestations of th...
A Study To Find Out Clinical Profile Of Liver Abscess
The liver abscess is a life threatening condition. We done this study to find out the clinical profile of the liver abscess . Total of fifty patients of liver abscess were included in the study , and data was collected...
A Prospective Study To Evaluate Alvarado Score In Acute Appendicitis
The present study has been conducted in Departments of Surgery and Pathology, S.N. Medical College & Hospital, Agra during a period from January 2011 to October 2012. Out of 47 patients 25 were males and 22 were female...