PATENTED PHARMACEUTICAL ORAL CONTROLLED RELEASE MATRIX SYSTEM
Journal Title: Journal of Biological and Scientific Opinion - Year 2013, Vol 1, Issue 3
Abstract
Oral controlled release drug delivery system becomes a very promising approach for those drugs that are given orally but having the high dosing frequency and shorter half-life. Matrix tablets serves as an important tool for oral controlled release dosage forms. Problems like patient compliance, drug targeting, local side effects, frequent administration and fluctuations in blood concentration levels, associated with their counterparts, the conventional dosage forms were rectified. Many of the pharmaceutical dosage form are formulated as sustained release dosage form to retard the release of a therapeutic agent such that its appearance in the systemic circulation is prolonged and its plasma profile is sustained in duration. Tablets offer the lowest cost approach to controlled and sustained release dosage forms. Matrix tablet as controlled release has given a new breakthrough for novel drug delivery system in the field of pharmaceutical technology. This review focuses on the various types of matrix systems based on polymer used and porosity of matrix system i.e. hydrophilic, hydrophobic, fat wax, porous, non-porous, pH sensitive. An effort has been made to consolidate different types of patents granted across the globe for last thirty years in the field of matrix system viz. tablet, pellets etc.
Authors and Affiliations
Neetu Khatri , Ajay Bilandi , Mahesh Kataria , Ankit Gupta
Keywords
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- EP ID EP109769
- DOI 10.7897/2321–6328.01328
- Views 119
- Downloads 0
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