Pathological and Microbiological Analysis of Cerebrospinal Fluid in Bacterial Meningitis
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2016, Vol 2, Issue 3
Abstract
Background: Meningitis is a life threatening infection with incidences increasing in adults and children. CSF analysis is a key tool to diagnose and differentiate between bacterial, viral, tubercular and fungal meningitis. Identifying the causative bacterial organisms is important to guide antimicrobial therapy. Aims & objectives: The present study was undertaken to analyze CSF parameters and to determine causative organisms of meningeal infection and also to find out their antibiotic susceptibility pattern. Settings and design: Cross sectional study. Methods and Materials: The study includes 100 clinically suspected cases of meningitis. Pathological and Biochemical analysis was done. Bacterial pathogens were identified by conventional methods of culture with sensitivity pattern. Results: Out of 100 cases, 30 cases showed total count >1000cells/ul with neutrophil predominance. 25 cases shows culture growth, with Escherichia coli as predominant organism isolated followed by Streptococcus pneumonia. Imipenem showed 100% sensitivity followed by Pipercillin/Tazobactum 90%. Conclusion: Our results of CSF fluid analysis revealed a total count of >1000 cells /ul with neutrophil predominance. Escherichia coli was the predominant organism isolated. Imipenem showed 100% sensitivity.
Authors and Affiliations
Ramesh S T, Girish Babu R J
Keywords
Related Articles
- EP ID EP228500
- DOI 10.17511
- Views 179
- Downloads 0
Histomorphologic spectrum of ovarian cystic lesions at a tertiary care centre
Introduction: An ovarian cyst is a liquid or semi-liquid material filled sac in an ovary. Proper management depends on the histomorphological division of non neoplastic & benign and malignant neoplastic lesions. So this...
Hemorrhagic Fever Viruses
Viruses causing hemorrhagic fever are broadly classified into five families as Arenaviridae, Bunyaviridae, Filoviridae, Flaviviridae & Rhabdoviridae. Some of them like Ebola virus can spread through aerosols and are cons...
A study of histopathological spectrum of non-malignant breast lesions
Background: Breast Lesions include a variety of Non-malignant and malignant lesions sometimes producing diagnostic difficulty for both Clinicians as well as Pathologists. In certain cases, histopathological examination,...
Two cases of spindle cell carcinoma with a histopathological review of biphasic tumours of head and neck
Spindle cell carcinoma (SPCC) is a very rare and unique biphasic variant of squamous cell carcinoma (SCC) which is a very rare malignancy of head and neck region.Spindle cell tumours are challenging feature of head and n...
The prevalence of the methicillin resistant staphylococcus Aureus in the postoperative wound infection in a South Indian hospital
Introduction: Objectives of the present study was to find the prevalence of methicillin resistant staphylococcus aureus at a South Indian hospital. Methods: Hundred clinically suspected cases of infected postoperative wo...