Pathological changes and clinical use of the measurement of serum/plasma concentrations of insulin-like growth factor type 1 (IGF-1) in horses, dogs and cats.
Journal Title: Human & Veterinary Medicine - International Journal of the Bioflux Society - Year 2010, Vol 2, Issue 2
Abstract
The biological effects of the growth hormone are in part mediated by the release of insulin-like growth factor type 1 (IGF-1) by the liver but also from other non-hepatic tissues. As opposite as GH, IGF-1 is not release in an episodic manner, is stable in the bloodstream and has a long biological halflife. As a consequence, the measurement of serum IGF-1 is an indirect way to measure GH. The present article reviews the alterations in serum IGF-1 concentrations in veterinary medicine, focused mainly in the diagnosis and prognosis of liver, heart, musculoskeletal, endocrine diseases and tumors. Some applications of the measurements of serum IGF-1 concentrations in sport horses are also provided.
Authors and Affiliations
Ana Muñoz, Cristina Riber, Pablo Trigo, Francisco Castejón
Keywords
Related Articles
- EP ID EP144968
- DOI -
- Views 90
- Downloads 0
Risk factors for post-acute myocardial infarction depression in elderl
Objective: To determine risk factors for development of post-acute ST elevation myocardial infarction (STEMI) depression in elderly. Material and Methods: We included 104 elderly patients diagnosed with STEMI. Clinical,...
Effect of potassium dichromate intake on feed intake and body weight, in female rats, Rattus norvegicus (exposure on three generations).
Material and methods: The experiments included three generations of female rats, each generation holding 28 White Wistar adult female rats, divided in 3 experimental (E) groups, exposed to 25ppmCr – LOAEL(E1), 50 ppm Cr...
Iron deficiency anemia: online methods of patient educatio
The authors present some of the most important online patient education methods in English on iron deficiency anemia (easy-to-read articles, information leaflets, easy-to-understand fact sheets, newsletters, patient...
Tubular carcinoid tumor of the appendix – a clinical cas
Objective: We present the clinical case of a young patient of 18 years old male, who was admitted in the surgical department of Cluj-Napoca County Hospital with symptoms of acute appendicitis. The appendectomy was perf...
Markers of severity of heart failure in the elderly.
Objective: To determine the possible correlation of NYHA classification with clinical and paraclinical parameters in elderly diagnosed with heart failure. Material and methods: Patients aged over 65 years, diagnosed with...