Pathological Profile of Wilms Tumour in a Pediatric Group Attending a Tertiary Care Hospital in North India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
Much of the early treatment of Wilms, tumour was unsuccessful because of the high mortality from the nephrectomy in the 19th century. Radiotherapy was first attempted in 1915, but by 1936, fewer than 20% of thePatients with wilms’ tumour survived. The objective was to study the staging and treatment modalities of Wilm’stumor. Wilms' tumor is the most common primary malignant renal tumor of childhood.& have varied clinical presentation. It is important to pick up the children with wilms' tumor earlier as early stages have excellent outcomes after treatment.A hospital based prospective study done with 25 diagnosed patients of Wilms tumour enrolled .All the patients were explained the complete protocol of the study and their informed written consent was taken. Study was carried out at Department of General Surgery of a Tertiary care. The peak incidence of Wilms' tumor was in 1 to 6 years age group (88%). Male: female ratio 2.5:1. The most common presentation was abdominal swelling (92%), followed by Pain abdomen (40%), haematuria (32%) and Fever (32%). As Per NWTS-4system, most patients presented in stage II (40%) followed by stage 1 (24%) & Stage 3(24%), Stage 4(12%).Most of the patients of Wilms' tumor presented within 1 to 6 years of age (80%) with abdominal swelling (92%) followed by Pain abdomen and haematuria.Male to female ratio in case of Wilms’ tumors is almost equal (2.5:1). Abdominal swelling was the common feature in Wilms’ tumor followed by Pain abdomen,hematuria and fever. Maximum cases of Wilms’tumor were in stage II. Maximum cases of Wilms’ tumor were treated with nephrectomy along with postoperativechemotherapy i.e. Vincristine and Actinomysin D in combination.
Authors and Affiliations
Dr. Zahida Akhter, Dr. Showkat Majeed, Dr. Rayees, Dr. M. Y. Wani, Dr. Sajad Hamid
Keywords
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