Periodontal Condition in Patients with Rheumatoid Arthritis: Effect of Anti-rheumatic Drugs
Journal Title: Journal of Dentistry, Shiraz University of Medical Sciences - Year 2019, Vol 20, Issue 3
Abstract
Statement of the Problem: Rheumatoid arthritis and periodontitis are chronic inflammatory diseases with a possible bidirectional relationship. This link may be affected by many factors like drug consumption. Purpose: This study was designed to evaluate the periodontal condition in patients with rheumatoid arthritis, considering the effect of disease modifying anti-rheumatic drugs. Materials and Method: This case-control study included 25 newly diagnosed rheumatoid arthritis patients with negative history of taking anti-rheumatic drugs, 25 patients who received anti-rheumatic drugs for more than three years and 50 healthy individuals as a control group. Periodontal indices, including plaque index, gingival index, probing depth, clinical attachment loss, and rheumatologic indices were recorded and compared between these groups. Results: Rheumatoid arthritis patients were significantly more affected by periodontitis compared with healthy subjects (p= 0.006). There was no significant difference in rheumatologic indices between patients with and without periodontitis. Clinical attachment loss in old rheumatoid arthritis patients and gingival index in newly diagnosed ones were significantly more compared to the control group (p= 0.003 and p< 0.001 respectively). We could not find a linear relationship between the severity of rheumatoid arthritis and chronic periodontitis (p= 0.1, r= -0.224). Conclusion: Periodontitis and clinical attachment loss were more in patients with rheumatoid arthritis than the healthy group, especially in drug consumers. Gingival index in patients without the history of consuming anti-rheumatic drugs was significantly higher than those who were drug consumers, indicating the effect of the medications on the signs of inflammation.
Authors and Affiliations
Samira Kordtabar, Mehrdad Aghaie, Elham Fakhari, Mohammad Ali Vakili
Keywords
Related Articles
- EP ID EP636093
- DOI -
- Views 76
- Downloads 0
Outcome of Surgery as Sole Treatment of Eosinophilic Granuloma of Jaws
Langerhans cell histiocytosis (LCH) is characterized by the congregation of proliferating langerhans cells (LC). Langerhans cells are a part of dendritic cell system of primary immune response that is responsible for pre...
Towards a New Era in the Management of Large Periapical Lesion in Permanent Tooth Using Stemcells: A 2-Year Clinical Application Report
Stem cells are considered as the principal source of differentiated cells. In the past few years, the research on the stem cell in various fields had shown success, but the stem cell-based therapies in the dentistry had...
The Effect of CuO Nanoparticles on Antimicrobial Effects and Shear Bond Strength of Orthodontic Adhesives
Statement of the Problem: Orthodontic appliances facilitate microbial plaque accumulation and increase the chance of white spot lesions. There is a need for new plaque control methods independent of patient's cooperation...
Effective Factors on Oral Health Behaviors of 12-year-old Children in Cities and Villages of Iran: a Path Analysis
Statement of the Problem: Oral and general health status depends on several factors such as the individual’s personal attributes, behaviors, and perceptions. Purpose: This study aimed to evaluate the factors affecting t...
Diagnostic Efficacy of Deeper Sections in Routine Oral Histopathology Practice: a Retrospective Study
Statement of the Problem: Histopathology is a gold standard diagnostic tool for oral lesions. Nonspecific and overlapping microscopic features often pose diagnostic challenges in routine practice. In such conditions, dee...