Pharmacogenomics: Applications in Drug Discovery and Pharmacotherapy

Abstract

Pharmacogenomics is the scientific study which explains individual variability of drug targets and to explore the genetic basis for such changes. With the completion of human genomic study, clear relation could now be established between the drug response in relation to a person’s genome. Pharmacogenomics, also known as personalized medicine, uses the person’s genome to determine the dose and dosage regimen, so that therapy could be optimized. As with the techniques like DNA microarray technologies person’s response to a therapy can be predicted and new therapies could be assigned. In the present review, the current technologies, and past significance has been discussed.

Authors and Affiliations

Hitesh Chopra , Sandeep Kumar , Vandana , Sandeep Arora

Keywords

Related Articles

Phytochemical Investigation and Pharmacological Evaluation of Solanum xanthocarpum Endowed with their potential Activity

The study was done to assess the in-vitro antibacterial potential of various extracts was studied and compared with ciprofloxacin as the standard and shows significant action against E. coli, B. substilis S. aureus, S. p...

Microneedle Mediated Vaccine Delivery: A Comprehensive Review

Microneedles can be representative for paradigm shift of drug delivery from patient non-compliant parenteral injections to patient compliant drug delivery system, which can be utilized for administration of vaccines part...

Preparation and Characterization of Phytosomal-Phospholipid Complex of P. Amarus and its Tablet Formulation

Present investigation was aimed at formulation, characterization and evaluation of phytosomal complex tablets for sustained delivery of Phyllanthus amarus complex. Phyllanthin, one of the active lignin present in this pl...

Pharmaceutical Analysis of Eptifibatide via Simple, Rapid, Economical UV-Spectrophotometric Methods

Eptifibatide is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Pharmaceutically it is applied to reduce the risk of acute cardiac ischemic events. The present work reveals two simple, rapid and econom...

Standardization of Some Commercial Anti-diabetic Herbal Products containing Syzygiumcumini

An isocratic HPLC method was developed for standardization of five commercially available products containing S. cumini seeds (DIABECON, MADHULENE, HYPONIDD, D-FIT and DIABEGON)using methylxanthoxylin (MXX)as marker. The...

Download PDF file
  • EP ID EP596684
  • DOI 10.15415/jptrm.2014.21004
  • Views 128
  • Downloads 0

How To Cite

Hitesh Chopra, Sandeep Kumar, Vandana, Sandeep Arora (2014). Pharmacogenomics: Applications in Drug Discovery and Pharmacotherapy. JOURNAL OF PHARMACEUTICAL TECHNOLOGY, RESEARCH AND MANAGEMENT, 2(1), 47-60. https://europub.co.uk./articles/-A-596684