Pharmacognostical and Pharmacochemical Parameters of Tablet Sutashekhara Rasa – Without Gold
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2015, Vol 3, Issue 1
Abstract
Tablet Sutashekhara Rasa (TSR) is an Ayurvedic, herbo-metal formulation prescribed widely for several conditions such as Acid peptic disorders, Pain in abdomen, Haemorrhage, Mental disorders etc. On analysis of pharmcodynamics of this compound it is basically Pitta corrective drug. Ardhavabhedaka (Migraine) is also one of the clinical morbidity which is manifested by vitiated Pitta/Rakta along with Vata. The available treatment in modern medicine is use of NSAIDs, Beta-blockers etc. with only temporary relief. TSR being a Pitta corrective is used in a clinical study with new indication in Ardhavabhedaka (Migraine). Till date there is no data available regarding evaluation ofTSR. Present study an attempt to develop newer approaches for the quality control and standardization of TSR. The samples were subjected to organoleptic, physicochemical analysis and Chromatographic (HPTLC) examination by optimizing the solvent systems. The phrmacognostical study of ingredients of TSR shows the presence of Sceleriform vessel, Lignified stone cells, Bottle necked shapedstone cells etc. Pharmaceutical analysis showed that the Average weight of tablet 276mg, Average hardness of tablet 2.05 Kg/cm2, Loss on drying 4.7904% w/w, pH value 7 and High Performance Thin Layer Chromatography at 254nm and 366nm resulted into 6 spots.
Authors and Affiliations
Mata Shweta P| Department of Pharma- Chemistry,Institute for Post Graduate Teaching And Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India, Vaghela D. B| Department of Pharma- Chemistry,Institute for Post Graduate Teaching And Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India, Dhiman K. S| Department of Pharma- Chemistry,Institute for Post Graduate Teaching And Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India, Harisha C. R| Department of Pharma- Chemistry,Institute for Post Graduate Teaching And Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India, Shukla V. J| Department of Pharma- Chemistry,Institute for Post Graduate Teaching And Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India
Keywords
Related Articles
- EP ID EP15239
- DOI -
- Views 388
- Downloads 13
Atypical presentations of congenital cutaneous candidiasis- presenting a cohort of 8 cases
Congenital cutaneous candidiasis is an extremely rare disorder that usually presents within the first 6 days of life. We report 8 neonates who presented with generalized skin eruptions within first 6 days of life, char...
Assessment of visual problems in elderly in an urban slum community of Mumbai
Background: Visual problems in the elderly share a major portion of the disability in the elderly. Visual impairment in the elderly can interfere with daily activities tremendously leading to dependence in many things....
Morphometric Approach towards Growth Performance of Mahseer (Tor tor) in River Narmada Near Hoshangabad (M.P)
During present study total 58 specimens of Mahseer (Tor tor) from River Narmada were studied for morphometric and meristic characteristics. Interrelationship among the morphometric and meristic characteristics were obs...
A study of clinical, metabolic and hematological profile in infants of diabetic mothers
Background:Diabetes has long been associated with maternal and perinatal mobidity and mortality. Infants of diabetic mothers (IDMs) have higher risks for serious problems during pregnancy, delivery and early neonatal p...
Knowledge, attitude, and perception of HIV / AIDS among married women
Background: In India, the rising prevalence of HIV among pregnant women is of great concern. Pregnant women are much receptive on health matters. So, it is important to assess their knowledge, attitude and perception r...