Pharmacological and Clinical Effects of Andrographis paniculata
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 4
Abstract
Andrographis paniculata is an herbaceous plant has been effectively used in traditional Asian medicines for centuries. The demand for the herbal drug treatment of various ailments is increasing day by day and plant drugs from the Ayurvedic system are being explored more in India as well as globally. The aerial part of the that plant is used. It contains a large number of chemical components like diterpene, diterpenoid, glycosides, flavonoids as well as flavonoid glycosides. Andrographolide has been reported to have a wide range of biological activities, such as anti-inflammatory, anti-allergic, anti-platelet aggregations, hepatoprotective and anti-HIV. A. paniculata polysaccharides combined with andrographolide can be used in the recovery of diabetic nephropathy. In addition to these activities the ethanol and an aqueous extract of A. paniculata also decrease blood glucose levels in normal rats and streptozotocin diabetic rats. Andrographolide, reacts with several inter and intracellular constituents like a bipolar compound hence ensuing in many biological responses.
Authors and Affiliations
Priyanka Gaur, Supriya Sharma, Sarika Pandey, Sandeep Bhattacharya, Surya Kant
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