Pharmacological evaluation of root and leaf extracts of Dracaena reflexa var. angustifolia
Journal Title: Innovations in Pharmaceuticals and Pharmacotherapy (IPP) - Year 2017, Vol 5, Issue 3
Abstract
Plants were being used in the treatment of diseases for centuries. In this work, Dracaena reflexa var. angustifolia, a traditionally significant plant has been studied for its potential medicinal properties. The nature has provided abundant plant wealth for all the living creatures, which possess medicinal virtues. Medicinal plants represent a rich source of antibacterial agents. There is a necessity to explore their uses and to ascertain their therapeutic properties. The present study aims to open new avenues for the improvement of medicinal uses of D. reflexa var. angustifolia leaves and roots are selected area for antibacterial and antioxidant activity. The methanolic extract of root and aqueous extract of leaves of D. reflexa var. angustifolia, Asparagaceae were assessed for its antibacterial and antioxidant activities. The antibacterial activity against Staphylococcus aureus, Enterobacter aerogenes, Proteus vulgaris, and Lacto bacillus organisms by agar cup plate method and aqueous leaf extract (ALE) exhibited an excellent antibacterial activity than methanolic root extract (MRE). The antioxidant activity of MRE was performed on isolated frog heart by H2 O2 induced oxidative stress method. In the present investigation the induction of cardiac arrest was observed at 15th, 25th, and 28 min H2 O2, ascorbic acid and MRE which shows the MRE possess a good antioxidant activity. ALE exhibited an excellent antibacterial activity than MRE. These findings suggest the excellent medicinal bioactivity of methanolic extract of root and aqueous extract of leaves of D. reflexa var. angustifolia, Asparagaceae and explain the popularity of this plant in the folk medicine as a remedy for bacterial disorders. The traditional system was proved to be more effective when compared to synthetic drugs due to a reduction in side effects
Authors and Affiliations
Narender B.
Keywords
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