Physicians’ opinion on the use of perazine in the treatment of mental disorders – results of the Delphi consensus study
Journal Title: Psychiatria Polska - Year 2012, Vol 46, Issue 6
Abstract
Aim. Currently, the use of first generation antipsychotics (FGA) is strongly limited. On the other hand, treatment with second generation antipsychotics (SGA) can not be applied in every patient. Therefore, there is an urgent necessity to obtain information about the knowledge and experience of clinicians with regard to safety and efficacy of pernazine, which represents the most widely used FGA in Poland. Due to a striking scarcity of studies on pernazine, authors designed and performed the study, which should provide physicians knowledge arising from daily practice of clinicians included in this study. Methods. Analysis was performed basing on 142 opinions of 26 physicians who were experienced in the treatment with pernazine. The Delphi method, which relies on concluding from expert opinions was adopted in this study. A three-round Delphi was used in order to yield final conclusions. Results. According to clinicians, pernazine is one of the most cost-effective and well-tolerated FGA. Furthermore, its different profiles of action (anxiolytic and sedative) enable to use pernazine in various indications, as well as in polypharmacotherapy. Referring to a long-term experience, clinicians emphasised the efficacy of pernazine and a high compliance with medication. Conclusions. Psychiatric treatment should be individualised taking into account not only clinical indices but also patient’s preferences and expectations. According to clinicians pernazine is a safe and versatile medication for schizophrenia or other mental disorders and serves as the alternative for SGA.
Authors and Affiliations
Tomasz Adamowski, Andrzej Kiejna
Keywords
Related Articles
- EP ID EP145946
- DOI -
- Views 97
- Downloads 0
Diagnostic difficulties in adolescent patients – subjective psychiatrist-side factors
Adolescence is a period of intensive development and crucial transitions in human life. Developmental crises, oppositional behaviours and non-adaptive patterns are strengthened. Simultaneously some symptoms of mental dis...
Etapy przebiegu choroby afektywnej dwubiegunowej
Koncepcja „stagingu” jako opisu klinicznego stopnia zaawansowania choroby jest szeroko rozpowszechniona i powszechnie stosowana w medycynie. W odniesieniu do choroby afektywnej dwubiegunowej (CHAD) model stagingu zakłada...
Psychotic experiences in the course of alcohol withdrawal symptoms: locus of control among patients with and without delirium and analysis of subjective experiences in delirium
Summary Aim. The comparison of the locus of control in groups of patients hospitalised due to alcohol withdrawal with and without delirium and analysis of psychotic experiences of patients with delirium. Methods. 25...
Sense of coherence and ways of coping in the relationship with brother or sister in healthy siblings of mentally ill persons
Aim . The aim of the present study was to investigate sense of coherence in healthy siblings of persons suffering from schizophrenia as well as their ways of coping in the relationship with ill brother or sister. Methods...
Bateria testów MATRICS – standard oceny funkcji poznawczych w badaniach klinicznych w schizofrenii
Deficyty w zakresie funkcji poznawczych stanowią grupę objawów schizofrenii, które często pojawiają się jeszcze przed pierwszym epizodem psychozy. Obejmują one głównie zaburzenia w zakresie uwagi, pamięci – w tym pamięci...