PHYTOCHEMICAL ANALYSIS, CHEMICAL CHARACTERIZATION AND ANTIOXIDANT ACTIVITY OF HELICANTHUS ELASTICA DESR
Journal Title: Indo American Journal of Pharmaceutical Sciences - Year 2018, Vol 5, Issue 2
Abstract
The objective of present studies deals with the Phytochemical analsis, chemical characterization and antioxidant activity of Helicanthus elastica Desr. Total phenolic content, Total flavonoid content, Total proanthocyanidin content of ethyl acetate fraction was determined. Antioxidant activity was carried out by Nitric oxide scavanging activity, DPPH scavenging activity, reducing power assay and anti-lipid peroxidation activity. Characterization of ethyl acetate fraction of H.elastica carried out by LC-MS/MS method. The HPTLC together with LC-MS/MS study confirm the presence of quercetin and epicatechin in ethyl acetate extract. Quantitative studies reveal that plant contains higher amount of phenolics such as flavonoids and proanthocynidins. Antioxidant activity in various in vitro models demonstrated that extract have significant radical scavenging as well as antioxidant activity which is consistent with its higher flavonoid content. Key Words: Helicanthus elastica, ethyl acetate fraction, characterization, flavanoid, antioxidant
Authors and Affiliations
Keywords
Related Articles
- EP ID EP267703
- DOI -
- Views 525
- Downloads 0
ESTIMATION OF DIFFERENT EXTRACTS OF AMARANTHUS VIRIDIS L FOR INVITRO ANTIOXIDANT ACTIVITY
Back ground: The plant Amaranthus viridis L (Amaranthaceous) is commonly known as “Never-fading flower” and “Slender amaranth” in Greek and English respectively. These plants have been traditionally used as antiulcer, an...
ESTIMATION OF XIPAMIDE BY USING HPLC IN PURE AND PHARMACEUTICAL DOSAGE FORM
A rapid and precise Reverse Phase High Performance Liquid Chromatographic method has been developed for the validated of Xipamide in its pure form as well as in tablet dosage form. Chromatography was carried out on Symme...
IN VITRO ANTIOXIDANT ACTIVITIES OF CHLOROFORM EXTRACT OF CTENOLEPSIS CERASIFORMIS
The sources of many of the new drugs and active ingredients of medicines are derived from natural products. The starting point for plant-based new drug discovery should be identification of the right candidate plants by...
ALZHEIMER’S – CURRENT STRATEGIES FOR ITS DIAGNOSIS AND TREATMENT
Alzheimer’s disease is the most prevailing type of dementia worldwide with pathological hallmarks as neurofibrillary tangles and amyloid β plaque. A large number of research and studies are undergoing to determine the ex...
COMMUNITY PREPARATION OF PEOPLE ON THE FRONTIER IN THE FACING OF MINING OPERATIONS
In many mining locations in Indonesia conflicts harmful to local people, have occurred due to misunderstandings and incomplete information received by groups of people in the community and/or the mining company. This pap...