Phytochemical and Antibacterial Activities of Combined Leaves and Flower Extracts of English Camphor Basil (Ocimum canum) on Some Selected Bacteria Associated with Skin Infections
Journal Title: International Journal of Contemporary Research and Review - Year 2018, Vol 9, Issue 6
Abstract
Phytochemical and antibacterial activities of combined leaves and flower extracts of English camphor basil (Ocimum canum) on some selected bacteria associated with skin infections was investigated.Plant samples were collected at Mista Ali, Bassa LGA of Plateau State. Phytochemical analysis was carried out in the Biochemistry Laboratory of National Veterinary Research Institute Vom (NVRI), located in Jos South LGA.The test organisms, S. aureus, S. pyogenes, P. aeruginosa, S. marcescens, E. faecalis were obtained from the microbial banks of bacteriology and dermatophilosis sections of NVRI, Vom and were standardized with a Nephelometer. Quantitatively,the leaves and flower ethanolic extracts were tested individually and in combination against bacteria associated with skin infections both extractsshowedthe presence of steroids, cardiac glycosides and flavonoids while tannins were detected in the leavesextract only. There was significant (p<0.05) variation in the quantity of inherent phytochemical components of the extracts. Cardiac glycoside had the highest concentrations (0.64±0.02 and 0.54±0.02) in the leavesand flower extracts respectively. Leavesextract showed activity against test bacteria except E. faecalis. Strains of S. pyogenesand S. aureuswere only susceptible to flower extract. The MBC rangedfrom 50-100mg/ml for the sensitive bacterialisolates. Fractional Inhibitory Concentration Index (FICI) from the combined extracts varied from 1.89 to 3.97 on the test bacteriathat showed lack of interaction (FICI<4). Thus, combination of leavesand flower of O. canummay not exhibit any advantage. However, theplant contain bioactive constituents of pharmacological significance and should be explore for more potentials
Authors and Affiliations
Gberikon G. M.
Keywords
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- EP ID EP546299
- DOI 10.15520/ijcrr/2018/9/06/534
- Views 61
- Downloads 0
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