Phytochemical and Pharmacological Screening of the Plant Crateva Magna Against Alloxan Induced Diabetes in Rats.
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2010, Vol 2, Issue 4
Abstract
The plant Crateva magna belonging to family Capparaceae is used in anti spasmodic, hypotensive, anti inflammatory, hypoglycemic, anti protozoal, analgesic purposes. The present study was carried out to evaluate the effect of Crateva magna whole plant (ethanolic and aqueous extract p.o.) on alloxan induced diabetes in appropriate animal model. The study was carried out on alloxan induced diabetic model. The diabetes was induced by using Alloxan and Glibencamide (5 mg/kg) was used as standard drug. The aqueous extract of leaves of Crateva magna results maximum yield value than that of petroleum ether extract, chloroform extract and alcohol extract through successive maceration process. The aqueous extract of leaves of Crateva magna showed maximum control of blood sugar in hyperglycemic Wistar rats than other experimental extracts. The test extract also reduces the blood sugar level to a maximum extent in case of normal animals. So we finally came to the conclusion that the plant Crateva magna increases healing of diabetes and prevents the development of experimentally induced diabetes in Wistar rats.
Authors and Affiliations
Prabhat Das , Ranjan Sethi , S. Mekap , S. Pani
Keywords
Related Articles
- EP ID EP160378
- DOI -
- Views 90
- Downloads 0
Thin Layer Chromatodraphy Method for the Determination of Ternary Mixture Containing Salbutamol Sulphate, Bromhexine Hydrochloride and Etofylline
Simple, rapid, accurate, precise, reliable and economical thin layer chromatographic and spectrophotometric methods have been proposed for the resolution and determination of Salbutamol sulphate (SS), Brombexine hydrochl...
Pharmacognostical standardization of leaves of Ixora coccinea, linn
Ixora coccinea Linn. is traditionally found to be useful for many ailments like hepatoprotective, Chemoprotective, antimicrobial, anti oxidant , antinociceptive and anti – inflammatory activities. The present study highl...
Management of Osteoporosis
Osteoporosis is a metabolic disease of bones that leads to bone fragility.70-80% of females and 20-30% of males will suffer a fracture related to osteoporosis in their lifetime. The current study identifies the causes of...
Evaluation of Diuretic activity from Tylophora indica leaves extracts
Aqueous and alcoholic extracts of Tylophora indica leaves were tested for diuretic activity in rats. The parameters studied on individual rat were body weight before and after test period, total urine volume,&...
Extracellular synthesis of silver nanoparticles using leaves of Euphorbia hirta and their antibacterial activities
Aqueous extract of shade dried leaves of Euphorbia hirta (L) was used for the synthesis of silver (Ag) nanoparticles. UV-visible spectroscopy studies were carried out to assess the formation Ag nanoparticles. Scanning E...