Phytochemical Screening and Toxicity Studies on the Leaves of Capparis sepiaria Linn. (Capparidaceae)
Journal Title: Journal of Basic and Clinical Pharmacy - Year 2010, Vol 1, Issue 1
Abstract
Capparis sepiaria Linn. (Family: Capparidaceae) is a rare indigenous in South India but has widespread distribution in many tropical and sub-tropical countries. The present study intended with various phytochemical screening and toxicity studies were carried out on the leaves of the Capparis sepiaria. Preliminary phytochemical evaluation of the ethanolic extract of revealed that the presence of reducing sugar, flavonoids, steroids, tannins, glycosides, alkaloids, gums, resins, amino acids, proteins and anthraquinones. The toxicity studies were performed as acute, sub-acute and chronic toxicity determined the LD50 value of 300-5000 mg/kg body weight 4-6 weeks. The results of the various phytochemical tests indicated that the plant to be rich in various biologically active compounds which could serve as potential source of the crude drugs and in addition the plant is not toxic to the experimental model.
Authors and Affiliations
P. Rajesh, V. Kannan, S. Latha
Keywords
Related Articles
- EP ID EP86454
- DOI -
- Views 173
- Downloads 0
EXPERIMENTAL EVIDENCE FOR THE ANTIDIABETIC ACTIVITY OF CAJANUS CAJAN LEAVES IN RATS
The antidiabetic activity of methanol leaves extract of Cajanus cajan (L.) Millsp. (Fabaceae) was studied in alloxan-diabetic and in oral glucose loaded rats. The acute toxicity and lethality (LD50) and the phytochemical...
ANTIHYPERGLYCEMIC EFFECT OF ETHANOLIC EXTRACT AND FRACTIONS OF ANACARDIUM OCCIDENTALE L. STEM BARK IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
The numbers of adults with diabetes in the world is estimated to rise 300 millions in the year 2025 and this leads to increasing search for better anti-diabetic drug. The effects of the ethanol extract (1.25g/kg) and fra...
Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. and Anacardium occidentale L.
Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed in blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels...
EFFECT OF EXTRACTS OF MURRAYA KOENIGII SPRENG.AND MORUS ALBA LINN. ON THE AGE OF ATTAINMENT OF PUBERTY AND OVARIAN FOLLICULOGENESIS IN RATS
An experiment was conducted to evaluate the effects of methanolic extracts of Murraya koenigii Spreng. (Curry leaf) and Morus alba Linn. (Mulberry leaf) on the age of attainment of puberty, relative ovary and uterus weig...
Role of liquid membrane phenomenon in the anti-bacterial activity of Cefuroxime Sodium
The role of liquid membrane phenomenon has been studied in the anti bacterial activity of cephalosporins i.e. Cefuroxime sodium. In our earlier publication [1] it was reported that hydraulic permeability data obtained to...