PHYTOCHEMICAL SCREENING, FLAVONOID CONTENT AND ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACT OF CEIBA PENTANDRA
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 2
Abstract
The seed of Ceiba pentandra collected from the rural area of Shirur, Pune district, were dried, milled and extracted with ether, ethanol and water. Phytochemical screening was carried out according to standard procedures. Carbohydrate & flavonoids, fixed oil, glycosides were found to be present in the aqueous, ether & alcoholic extract resp. Total Flavonoid content was determined by spectrophotometric methods and that was found to be 2.56 g & 2.20g quercetin equivalent per 100 g of ethanolic & water extract resp. In-vitro antioxidant activity of ethanolic seed extract of Ceiba pentandra was determined by DPPH free radical scavanging assay. All the analysis was made with the use of UV-Visible Spectrophotometer (Jasco V-530). The ethanolic seed extracts of Ceiba pentandra had shown very significant DPPH (1, 1-diphenyl-2-picryl-hydrazyl) radical scavenging activity compared to standard antioxidant. The DPPH radical scavenging activity of the extract was increased with the increasing concentration. In DPPH free radical scavanging assay IC50 value of ethanolic seed extracts of Ceiba pentandra was found to be 50.33±5.29 as compared with standard ascorbic acid (44.93±2.92 µg/ml).
Authors and Affiliations
Mohan Agrawal , Sagar Sanap , Bhanu Priya, Bhagyashri Talole
Keywords
Related Articles
- EP ID EP135655
- DOI -
- Views 102
- Downloads 0
DEVELOPMENT AND EVALUATION OF THEOPHYLLINE MICROBALLOONS DRUG DELIVERY SYSTEM
The objective of the present investigation was to prepare theophylline microballoons loaded with sodium alginate, eudragit S 100 and sodium bi-carbonate as gas generating agent. The microballoons prepared by ionotropic...
CLINICAL EVALUATION OF KODIPAVALA CHUNNAM IN THE TREATMENT OF INFECTIVE HEPATITIS, DRUG INDUCED HEPATITIS AND ALCOHOLIC HEPATITIS
The present clinical study was carried out to validate the efficacy and safety of Siddha Herbo- mineral formulation ‘Kodipavala Chunnam’ in the treatment of Infective hepatitis, Drug induced hepatitis and Alcoholic hepat...
TRAPA NATANS (WATER CHESTNUT): AN OVERVIEW
Trapa natans (water chestnut), commonly known as singhara in India, belonging to family Trapaceae, is a free-floating plant which grows in shallow water fields, ponds or swampy land. The water chestnut is native to Europ...
TOXICOLOGICAL STUDIES OF THE AQUEOUS EXTRACT FROM BRILLANTAISIA VOGELIANA (NÉES) BENTH. (ACANTHACEAE)
Brillantaisia vogeliana (Acanthaceae) is used in folk medicine in the West region of Cameroon to manage obesity. In this study, we investigated the toxic effect of the aqueous extract of B.v. in rats. Three doses of...
EVALUATION OF ANTIMUTAGENIC POTENTIAL OF RIPE AEGLE MARMELOS FRUIT EXTRACT USING MICRONUCLEUS AND CHROMOSOMAL ABERRATION ASSAY IN MOUSE BONE MARROW
The present study was designed to evaluate the antimutagenic potential of ripe Aegle marmelos fruit, using micronucleus and chromosomal aberration assay in mouse bone marrow. The antimutagenic effect of 50% methanolic ex...