Pilot Study to Evaluate the Effect of Vitamin E Supplementation on the Menopause Rating Scale Scores among Perimenopausal Women
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Post- Women’s Health Initiative trial, Hormone Replacement Therapy (HRT) has fallen into disrepute. Other alternative therapies are being explored for the management of menopausal symptoms. We conducted a pilot study to evaluate the efficacy of vitamin E in the management of menopausal symptoms among perimenopausal women. Material and Methods: A prospective randomized placebocontrolled single-blinded study was conducted. Thirty perimenopausal women aged between 35-50 years, who declined hormone replacement therapy for menopausal complaints were enrolled for the study. The selected patients were randomly distributed into two groups A and B. Group A (n=15) was given 800 IU of vitamin E per day in two divided doses for a period of three months while group B (n=15) was given placebo (soft gel capsules) orally once daily for three months. The Menopause Rating Scale (MRS) was used to evaluate the response to treatment. Paired t-test and independent t-test were applied for statistical analysis. Results: Among the vitamin E administered group, the somatic and psychological scores improved by 22.44% (p<0.05) and 14.63% (p<0.01) respectively. Somatic and psychological scores also improved significantly among those on placebo treatment. The urogenital subscale scores did not improve among both the groups. Though the total scores improved by 18.34% (p<0.05) among vitamin E group, it was not significantly different from the 13.64% (p<0.05) total score improvement seen in the placebo group. Conclusion: Vitamin E was not superior to placebo treatment for management of menopausal symptoms.
Authors and Affiliations
Marya Ahsan, Ayaz Khurram Mallick, Raj Ranjan Prasad
Keywords
Related Articles
- EP ID EP426830
- DOI -
- Views 104
- Downloads 0
Small Bowel Obstruction Secondary to Femoral Hernia
Introduction: 2% to 4% of groin hernias are femoral hernias. They are more common in females. They usually present in emergency department when get strangulated and require emergency surgery. This presents with symptoms...
Comparative Study between Fistulectomy and Seton in Fistula in ANO Regarding Healing and Postoperative Complications
Fistula in Ano forms a good majority of treatable benign lesions of rectum and anal canal. Fistula in ano rarely heals spontaneously and requires surgical therapy to achieve a cure. It has been said that more surgeons re...
Cutaneous Manifestations of Internal Malignancy
Malignancy inside the human body manifests as cutaneous disorders which a person was not aware of. Many of the Dermatological lesions are overseen by dermatologists and dentists in the diagnosis of various autoimmune dis...
A Study on Culture and Sensitivity Pattern in Urinary Tract Infections of Febrile Children
Introduction: Urinary tract infection (UTI) is one of the most common source of infection in febrile children under 5 years of age. Early diagnosis and appropriate treatment can significantly decrease late serious compli...
Evaluation of Heavy Metal Levels in the Serum of Breast Cancer Patients in Port Harcourt, Nigeria
Introduction: Breast cancer is a form of cancer that originates from the breast tissue. It’s a disease where cells in the breast grow swiftly and advance beyond regulation. Heavy metals such as copper (Cu), chromium (Cr)...