Plasmodium vivax causing pancytopenia after allogeneic blood stem cell transplantation in CML.
Journal Title: Bone Marrow Transplantation - Year 1998, Vol 22, Issue 2
Abstract
A 20-year-old male patient with chronic myeloid leukemia (CML), in chronic phase, underwent allogeneic blood stem cell transplantation in August 1996. Engraftment was well documented in the marrow on day 19, but pancytopenia and mild splenomegaly continued. On day +70, the patient developed severe anemia and had one pyrexial episode. He was detected to have malaria (Plasmodiium vivax). After chloroquin therapy, the pancytopenia reversed completely. We suggest that malaria should be considered as a possible cause of pancytopenia in the post-transplant period in endemic areas.
Authors and Affiliations
V Raina, A Sharma, S Gujral, R Kumar
Developing an algorithm of informative markers for evaluation of chimerism after allogeneic bone marrow transplantation.
Analysis of chimerism by polymerase chain reaction amplification of STR or VNTR has become a routine procedure for the evaluation of engraftment after allogeneic stem cell transplantation. Knowledge of the frequency of d...
Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies.
The purpose of this study was to evaluate the feasibility and efficacy of allogeneic hematopoietic stem cell transplantation with a reduced-intensity regimen (RIST) in patients with acute myeloid leukemia (AML) or myelod...
Plasmodium vivax causing pancytopenia after allogeneic blood stem cell transplantation in CML.
A 20-year-old male patient with chronic myeloid leukemia (CML), in chronic phase, underwent allogeneic blood stem cell transplantation in August 1996. Engraftment was well documented in the marrow on day 19, but pancytop...
Role of HLA in hematopoietic SCT
HLA disparity between hematopoietic stem cell (HSC) donor and recipient triggers T-cell and NK-cell allorecognition, and induces the GVHD, GVL effect and/or may cause an engraftment failure. This review will cover the sc...