Polyneuropathy developing after infliximab therapy in a patient with recalcitrant pyoderma gangrenosum
Journal Title: Türkderm - Deri Hastalıkları ve Frengi Arşivi - Year 2019, Vol 53, Issue 1
Abstract
The use of tumor necrosis factor-alpha (TNF-α) inhibitors has increased tremendously during the recent years. Neurological side effects associated with TNF-α inhibitors are rarely encountered, but these side effects may result in serious clinical problems. Treatment with TNF-α inhibitors is associated with demyelinating syndromes which can affect both the central and peripheral nervous systems. Short-term follow-up indicates relatively good outcomes, sometimes after just treatment discontinuation, although corticosteroids or intravenous immunoglobulin may be necessary to reverse the conditions in some cases. Here, we present a case of motor neuropathy developing after treatment with infliximab in a patient with recalcitrant pyoderma gangrenosum.
Authors and Affiliations
Ralfi Singer, Cihat Örken, Şule Güngör, Mehmet Çopur, Utkan Kızıltaç, Kübra Kızıltaç, Emek Kocatürk Göncü, Selma Şengiz Erhan
Keywords
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- EP ID EP538143
- DOI 10.4274/turkderm.galenos.2018.70437
- Views 89
- Downloads 0
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