Post-operative analgesic efficacy of fentanyl via different routes – A comparative study of nebulisation, intranasal and intravenous routes
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 6
Abstract
Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hospital stay, and increasing the incidence of admissions after surgery. Study was done to assess and compare the post-operative analgesic effects of fentanyl via nebulisation, intranasal and intravenous routes to provide better analgesia, anxiolysis and sedation to the patient. Materials and methods: After approval from ethical committee of SPMC, Bikaner and written informed valid consent from patients, sixty patients of either sex belonging to ASA class I and II, were randomised into three group (Group I - Nebulised Fentanyl, Group II - Intranasal Fentanyl, Group III - Intravenous Fentanyl). With all aseptic precaution, subarachnoid block was instilated via 23/25 gauze spinal needle by injecting sufficient dose of bupivacaine heavy 5% to achieve an adequate sensory and motor block for the proposed surgery. When patient complained pain 1st time, fentanyl was given via nebulisation in group I, intranasal in group II, and intravenous in group III with dose 4 mcg/kg, 1.5 mcg/kg, 2 mcg/kg respectively. Patients were assessed for pain by VAS score. For statistical data, SPSS 10.0 software was used. Results: In present study, Ramsay sedation score, patient satisfaction score and duration of analgesia was better in group II as compared to group I and III. Group III had lesser time of onset of analgesia in comparison to group II and I respectively. Conclusion: On the basis of analgesic efficacy, we concluded that intranasal group was better than nebulisation and intravenous route.
Authors and Affiliations
Raghvendra Singh, Anita Pareek, Meera Kumari, Mohammad Yunus Khilji, Prashant Sirohiya
Keywords
Related Articles
- EP ID EP428790
- DOI -
- Views 85
- Downloads 0
Cholecystectomies – A 1.5 year histopathological study
Background: The gallbladder is a surgically important organ of the body which may be affected by a variety of pathological processes, which are often, under appreciated. It has a wide spectrum of diseases ranging from co...
Spectrum of gynecological disorders in elderly women
Introduction: Postmenopausal phase is important that primary care clinicians be aware of common gynecologic concerns and the potential impact of these on the function and quality of life of older women. Aim: This study...
Acardiac twin - A case report
Acardiac twinning is a rare congenital anomaly of monozygotic twin pregnancy which often results from abnormal placental vascular anastomosis. It leads to twin reversal arterial perfusion with complex pathophysiology. Cu...
Evaluation of the sedative and anxiolytic effects of Midazolam and Clonidine as oral premedicant in paediatric patients undergoing elective surgery under general anaesthesia
Background: The preoperative period is stressful in the paediatric patients; oral premedications make the experience of anaesthesia and surgery more pleasant and less traumatic. Aim: To evaluate and compare the effects...
Study of profile of cardiac dysfunction in HIV infected children
Background: There are very few published studies of heart disease in HIV infected children. The incidence of cardiovascular disease reported among HIV infected children ranges from 72% to 90%. Cardiac disease was primary...