Potential of Drug-Drug Interaction in Polypharmacy Prescription: Retrospective Study on a Drugstore in Bandung
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2016, Vol 5, Issue 4
Abstract
Polypharmacy prescription very commonly occurs on prescribing the outpatient and inpatient in every health facility. Polypharmacy may increase the risk of Drug-drug Interactions (DDI’s) which mostly causes harm impact in the patient’s therapy. The aim of this study was to measure the potential of DDI’s on the outpatient prescription in one of the drugstore in Bandung. The data was processed through www. drugs.com database or Drug Interactions Checker. This study described the prevalence and classification of potential interactions based on interaction level of major, moderate, and minor. The number of outpatient prescription on January–March 2014 was 352 sheets of prescriptions with 1.111 R/. From overall numbers of prescriptions, there were 197 (55.97%) sheets of prescriptions on inclusion criteria. In 121 prescriptions, there were 34.38% of DDI’s potential. All of DDI’s potential occurs was 194 interactions. The major DDI’s potential of 25 (12.89%), moderate of 134 (69.07%) and minor of 35 (8.04%). The most of DDI’s found in major and moderate level need more attention and prevention aid against DDI’s potential that may occur by doctors and pharmacists to maximize the effectiveness of patient’s therapy.
Authors and Affiliations
Sulastri Herdaningsih, Ahmad Muhtadi, Keri Lestari, Nurul Annisa
Keywords
Related Articles
- EP ID EP368904
- DOI 10.15416/ijcp.2016.5.4.288
- Views 117
- Downloads 0
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