Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract
Journal Title: Здоров`я дитини - Year 2017, Vol 12, Issue 7
Abstract
Bacteriocins are ribosomal-synthesized hydrophobic antimicrobial peptides with a broad antimicrobial spectrum of action. Gram-positive bacteria are the main source of bacteriocins. Bacteriocins of different classes acting on Gram-positive and Gram-negative bacteria use different molecular mechanisms, the functioning of which leads to disruption of the integrity of the cell wall or inhibition of the synthesis of nucleic acids and proteins of targeted bacteria. Currently, more than 100 lantibiotic peptides are described in the literature. Many of them are used to develop future medicines. Several lantibiotics are currently undergoing clinical and preclinical trials, including bioengineering lantibiotics, which can play a key role in overcoming the antibiotic resistance of bacterial pathogens.
Authors and Affiliations
А. Е. Abaturov, Т. А. Kryuchko
Keywords
Related Articles
- EP ID EP249233
- DOI 10.22141/2224-0551.12.7.2017.116187
- Views 88
- Downloads 0
Medical and Rehabilitation Centers in Children’s Houses — New Opportunities for Treatment and Rehabilitation of Children
The article presents data on the opening of medical and rehabilitations centers at the children’s houses of Donetsk region. Approaches, terms, possibilities and methods of rehabilitations used during the treatment and re...
Adverse Events Following Immunization
.
Modern features of complementary feeding and their efficiency in baby-led feeding
Background. Baby-led feeding exists in the practice of pediatrics since 2002. But there are still no clear results on the effectiveness of its implementation and the impact on the health of young children. Particular att...
Early Neonatal and Postnatal Diagnostics, Clinical Manifestations, Treatment and Prognosis by Atrial Septal Defect
The article presents the published data on the prevalence, the main clinical manifestations, modern methods of early neonatal and postnatal diagnosis, treatment and prognosis by atrial septal defect — the congenital mal...
The Mechanism of Action of the Activated Nitrogen-Containing Metabolites in the Respiratory Tract. Proinflammatory Effect (Part 2)
The review of literature presents modern data about antibacterial and antiviral effect of nitrogen monoxide. Bactericidal action of nitric monoxide in the phagosome, involvement of nitrogen monoxide in the development of...