Pragmatic clinical trial in trauma: crash 2 trial in Peru
Journal Title: Revista Peruana de Medicina Experimental y Salud Publica - Year 2008, Vol 25, Issue 1
Abstract
CRASH-2 is a pragmatic clinical trial which evaluates the efficacy of a widely available, low cost antifibrinolytic for the prevention of mortality and bleeding in patients with trauma. In this article we present some issues related to the magnitude of the problem as well as the need for research in trauma relevant to the Peruvian context. The rationale for the CRASH-2 trial and the Peruvian experience up to date are also discussed.
Authors and Affiliations
Alonso Soto, Elfi Torres, José Caballero, Wenceslao Azabache-Puente, César Malca-Polo, Marco Gonzáles-Portillo, Diana , Rodríguez-Hurtado, Juan Vélez-Temoche, Edgar Núñez-Huerta, Anselmo Moya-Charcape, Jorge Flores del Pozo, Pedro Lagos-Poma, Hernán Cruz-Yupanqui, J. Jaime Miranda
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