Presence of bla TEM and bla SHV Genes in ESBLs Producing Klebsiella Pneumonia among Female Patients in University of Benin Teaching Hospital
Journal Title: International Journal of Research and Review - Year 2017, Vol 4, Issue 5
Abstract
This project was carried out to determine the presence of blaTEM and blaSHV genes in ESBL producing Klebsiella pneumonia from urogenital tract of female patients at UBTH. The specific objectives of the study were: (i) to isolate the multi drug resistant strains of Klebsiella pneumonia in urogenital tract of female patient at UBTH,(ii) to identify and characterize ESBLs in the multi-drug resistant Klebsiella pneumonia strains.(iii) to determine what fraction of potential ESBL producers go on to be confirmed.(iv) to determine what fraction of the isolates are hospital or community acquired. Isolates where taken from women who had urogenital infection from both the inward and outward patients, a total of 200 (two hundred) klebsiella pneumoniae isolates which was broken into 100 (one hundred) inward patients and 100 (one hundred) outward. Table 2.0 shows the biochemical identification of the isolates, Klebsiella pneumoniae is a lactose fermenter, it is a motile organism, citrate and urease positive, utilizes glucose to produce acid and gas, indole negative and Hydrogen sulphide negative. The emergence and provocative prevalence and its continuous spread of ESBL-producing Klebseilla pneumonia strains in this study are worrisome which brings to the ineffective usage of Cephalosporins against these isolates. More new antibiotics are drum rolled to inhibit the production of these enzymes such agents like clavulanic acid has been over powered by their over production of the enzymes bringing challenges to pharmacotherapeutics. Although imipenem is the drug of choice for serious infection disease these days, prolong and extensive use of this drug in treatment of infection caused by resistant isolates would be enhanced as there is newer evidence of imipenem resistance.
Authors and Affiliations
Ajayi Amanda Esohe
Keywords
Related Articles
- EP ID EP366959
- DOI -
- Views 79
- Downloads 0
Concept Mapping Enhancing Learning in Health Professionals
Concept mapping is an educational tool that encourages meaningful learning. Teaching is challenging in undergraduate medical education, particularly because it is based upon imparting lectures and rewarding for recall of...
The Influencing Factors of Competitiveness in Small and Medium Enterprises in Indonesia
SMEs (Small and Medium Enterprises) plays important role in national economy. It is shown by development of small enterprises in Indonesia, especially in rural such as Songkok centre. The role of marketing becomes very i...
Adverbs in Karonese
This article describes about the use and functions of adverbs in Karonese language. Adverbs in Karonese language describes the meaning of the whole sentence and describe the meaning of the sentence elements in a sentence...
Development of Mathematics Learning Devices Oriented on Problem-Based Learning Model to Improve Critical Thinking Ability of Students in Across of Sma Kuala Nagan Raya Aceh
This study aims to produce mathematics learning devices which are valid, practical and effective through the Problem-Based Learning model to improve critical thinking in across of high school students in Kuala Nagan Raya...
Syndrome X, C - Reactive Protein and Proteinuria in Newly Diagnosed Patients of Type 2 Diabetes Mellitus: A Cross-Sectional Study
Introduction: Diabetes Mellitus (DM) is the commonest metabolic abnormality in the world. Type 2 diabetes, the commonest form of diabetes constitutes nearly 90% of diabetic population in any country. The Syndrome X consi...