Prevalence and Antibiogram of Methicillin Resistant Staphylococcus aureus Isolates in a Tertiary Care Centre of Western Uttar Pradesh
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
Methicillin resistant Staphylococcus aureus (MRSA) infections have emerged as one of the most common healthcare acquired infections in the present era. In this study, we report the prevalence and antibiotic susceptibility pattern of MRSA isolates from various clinical samples in a tertiary care hospital. Various clinical specimens from both outpatients as well as admitted patients were cultured on the suitable culture media and Staphylococcus aureus was identified using standard tests like catalase test, slide and tube coagulase test. All Staphylococcus aureus isolates were tested for their antibiogram pattern by Kirby - Bauer disc diffusion method and MRSA were identified amongst them following CLSI guidelines. The Dtest was performed on all Staphylococcus aureus isolates to identify erythromycin induced clindamycin resistance. The prevalence of MRSA in our study was found to be 60.87%. Linezolid and vancomycin proved to be effective against 96.4% and 100% of MRSA isolates respectively.. Antibiotics with highest resistance against MRSA isolates were penicillin, quinolones (ciprofloxacin, levofloxacin) and ampicillin. Also, 32.14% of MRSA isolates and 22.22% of MSSA isolates showed erythromycin induced clindamycin resistance in this study. Regular surveillance of hospital associated infections along with strict infection control measures, monitoring antibiotic susceptibility pattern of all MRSA isolates and formulation of definite antibiotic policy should be implemented in the hospitals as control measures against MRSA infections.
Authors and Affiliations
Dr Vijay Prakash Singh
Keywords
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