Prevalence and Antibiotic Sensitivity Pattern of Bacteria Isolated from Nosocomial Infections in Respiratory Intensive Care Unit of a Teaching Tertiary Care Health Facility
Journal Title: Scholars Academic Journal of Biosciences - Year 2014, Vol 2, Issue 11
Abstract
In India, nosocomial infections (NIs) in patients admitted to intensive care units are recognized as a significant problem. The rate of NIs is two to five times higher in intensive care units than that of the general inpatient population. The aim of the present study was to know the prevalence and antibiotic susceptibility pattern of bacteria isolated from patients suffering from NIs admitted in Respiratory intensive care unit (RICU) of our hospital. The present study was designed to carry put prospectively for duration of two years (2008-2010). Hundred patients on mechanical ventilation of all age groups and sex admitted to RICU and suffering from NIs were included in the study. Various samples like endotracheal secretions, blood, urine, pus and post-operative wound swabs were collected aseptically and processed. Antibiotic susceptibility pattern of bacterial isolates was tested by Modified Stokes method. Environmental samples from various surfaces were collected periodically to assess the possible reservior of nosocomial infections. 184 (92.9%) gram-negative and 14 (7%) gram-positive bacterial pathogens were isolated. Most frequently isolated organism was P. aeruginosa 48/184 (26%). The second most common organism was Acinetobacter baumannii 42/184 (22.8%). Imipenem and meropenem were found to be most effective drugs as 78% and 72.1% gram-negative bacteria and 81.3% and 62.5% of P. aeruginosa strains were sensitive to these antibiotics respectively. Majority (98.4%) of the isolates showed resistance to three or more than three drugs. Regular monitoring of the resistance pattern of bacterial pathogens from ICU patients is needed to prescribe appropriate treatment.
Authors and Affiliations
Rama Sikka, Sarla Hooda, Pooja Singla, Shamlal . , Antariksh Deep, Uma Chaudhary
Keywords
Related Articles
- EP ID EP378626
- DOI -
- Views 74
- Downloads 0
Phenotypic variation in F1 population of inter-varietal crosses of Coffea arabica L.
Most of the commercially cultivated coffee varieties are heterogeneous in nature and produce variation in the plant population in further generation for phenotypic characters. Use of such varieties in crossing leads to b...
High Performance Liquid Chromatographic Determination of Residue pesticides in Samples of Apple, Cucumber, Guava, and Garden Egg
It has been established that certain foods, such as fruits and vegetables, contain high levels of pesticide residue; contaminated with pesticides during pre- and post-harvest. In order to avoid health risks to consumers,...
The Effect of Human Umbilical Cord Blood Mesenchymal Stem Cells on the Expression of Leukaemic Inhibitory Factor (LIF) and Interleukin-10 (Il-10) in Acute Myeloid Leukaemia (AML)
Haematological malignancies represent approximately 7% of all malignant diseases. Acute myeloid leukaemia (AML) is an aggressive and fatal disease. AML treatment basically remained unimproved in the last 20 years; it dep...
Infertility in The Philippines and Natural Procreative (Napro) Technology: A Commentary
Abstract: The latest retrievable data about infertility in the Philippines was made available to the public by Merck Serono, a private pharmaceutical company who commissioned the survey in 2011. The survey was conducted...
Prevalence and Antibiotic susceptibility pattern of Klebsiella pneumoniae isolated from various clinical specimen in a tertiary care hospital of Tripura.
Abstract: Klebsiella pneumoniae are common causative agents of nosocomial and community acquired infections and are leading causes of morbidity and mortality. This study gives an account of isolation of Klebsiella pneumo...