Prevalence and antimicrobial susceptibility pattern of clinical isolates of Methicillin-resistant Staphylococcus aureus in a tertiary care hospital in Mangalore
Journal Title: Journal of International Medicine and Dentistry - Year 2016, Vol 3, Issue 3
Abstract
Staphylococcus aureus is the most common human bacterial pathogen and is an important cause of nosocomial infections. Due to inappropriate use of antibiotics, the resistance in these strains is increasing worldwide. In India, Methicillin-resistant Staphylococcus aureus(MRSA) represents a challenge for all healthcare institutions. This study was carried out to determine the prevalence of MRSA in a tertiary care hospital and the prevalent antibiotic susceptibility patterns. Fifty strains of MRSA were taken up for the study. Methicillin resistance was detected by Cefoxitin Disk Diffusion test. A prevalence rate of 46% for MRSA was seen in our study. The most effective antibiotics were Linezolid (100%), Teicoplanin (96.6%) and Vancomycin (96.6%). This study highlights the fact that MRSA continues to be a problem in healthcare institutions. With MRSA rates being high, routine and regular surveillance of MRSA and in vitro susceptibility testing, regular monitoring and update of infection control practices and antibiotic policies might change the prevailing trends and reduce the chances of MRSA infections.
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