Prevalence of Glaucoma among Family Members of Glaucoma Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 11
Abstract
Background: Epidemiologic findings in the Baltimore Eye Survey maintained that POAG family history indicates an important risk factor for disease development. The Barbados Eye Study also suggests that people more vulnerable to developing POAG are elderly males with a family history of glaucoma. Primary Open Angle Glaucoma is known to be hereditary although the exact mode of transmission has not been determined. Primary open angle glaucoma is more prevalent among eyes with Exfoliation Syndrome (14%) than among eyes without Exfoliation Syndrome (2%). Objectives: The purpose of the study is to detect glaucoma in family members of the patients with established Primary Open Angle Glaucoma in Kashmir Valley Materials and Methods: This observational study was conducted in the Department of Ophthalmology, Government Medical College, Srinagar which is the tertiary care centre in the valley. The study was conducted for a period of one and a half year in Family members of diagnosed cases of glaucoma (POAG) Results: 100 Family members (first degree relatives) of diagnosed primary open angle glaucoma were screened for the presence of glaucoma. 57% (57 Members) were male and 43% (43 Members) female. The study group consisted of 50% (50) siblings, 48% (48) children and 2% (2) Parents. The overall prevalence of glaucoma in first degree relatives was 12%. No significant gender preponderance was found. The mean age for glaucoma was higher (52.17±8.726 years) than that for no glaucoma (45.32±4.471 years). The prevalence of glaucoma was 100% (2 members) among parents, 14% (7 members) among siblings and 63% (3 members) among children. The prevalence rate of glaucoma increases with increasing age, the prevalence being 6.5% in the age group of 40-49years, 23.8% in the age group of 60-79years. Glaucomatous involvement was bilateral in all the members but the severity of damage was asymmetric. Average Retinal Nerve Fiber Layer (RNFL) thinning on Optical Coherence Tomography (OCT) was seen in all the 12 members (100%) in both eyes. Right eye showed borderline thinning in 3 members, early thinning in 5 members, moderate thinning in 3 members and severe thinning in 1 member whereas Left eye showed borderline thinning in 1 member, early thinning in 7 members, moderate thinning in 3 members and severe thinning in 1 member. Conclusion: Primary open angle glaucoma is more common in family members of Primary open angle glaucoma patients.
Authors and Affiliations
Dr Farooq Ahmed Runyal
Keywords
Related Articles
- EP ID EP507305
- DOI -
- Views 46
- Downloads 0
Predictors of Relapse in Steroid Sensitive Nephrotic Syndrome
Background: Nephrotic syndrome affects 1-3 per 100,000 children below 16 years. The majority of children have steroid sensitive nephrotic syndrome (SSNS) with a favorable prognosis, 10% do not respond and hence defined a...
Study of NT-Pro BNP in Acute Coronary Syndromes
Background: Acute Coronary Syndrome is one of the commonly diagnosed life threatening condition as of now. Hence it is necessary to diagnose early and assess the severity of disease as soon as possible. This study is don...
Case Report of Giant Phyllodes
Phyllodes tumours are rare breast tumours. These fibro-epithelial neoplasms are classified as benign, borderline & malignant based on stromal & cellular patterns, but a reliable classification is challenging. The diagnos...
The Relationship between Healthy and Clean Life Behavior and Hepatitis A Incidence in Children of Rural Areas
Background: One of the infectious diseases that still become a priority in Indonesia is hepatitis A. Objectives: This study aimed to obtain information on a relationship between a clean and healthy life behavior that is...
A Comparative Study of Propofol and Thiopentone with local Anaesthetic Spray as Inducing Agents for I-Gel Insertion
Aim: Of the study is to compare insertion conditions for I gel using propofol and thiopentone with lignocaine spray as inducing agents in terms of haemodynamic stability as well as in terms of no of insertion attempts, s...