Prevalence of Group A Streptococcal Carriage Rate in Asymptomatic Children

Journal Title: National Journal of Laboratory Medicine - Year 2019, Vol 8, Issue 2

Abstract

ABSTRACT Introduction: Streptococcus pyogenes is a Gram positive cocci causing respiratory infections commonly in children. Throat carriers are children in whom the organism is isolated from throat swab specimens in the absence of symptoms. This study was conducted in the institution to screen children for the detection of pharyngeal carriage rate of Group A Streptococci (GAS) and to compare the efficiency of two different methods for the diagnosis of S.pyogenes. Aim: To study the prevalence of Group A Streptococcal carriage rate in throat swabs of children. Materials and Methods: This is a prospective study conducted from March 2018-June 2018 (4 months) on 100 asymptomatic children attending the Pedodontics OPD of a self financing Dental College and Hospital. Two throat swabs were collected for bacteriological culture and rapid strip testing for detection of S.pyogenes was done. Results: Out of 100, 64 children (64%) were found to be in the age group between 6-10 years. Fourteen (14%) of the children showed growth of Streptococcus pyogenes on culture and 18 of them (18%) were positive by the rapid test method. Rapid test strips were found to be 85.7% sensitive and 93% specific for the detection of GAS carriage. Conclusion: Determination of carrier rate is important though there are no recommended guidelines for aggressive treatment of carriers. Throat culture remains the gold standard investigation for isolation of Streptococcus pyogenes, but Rapid antigen detection kits have proved to be valuable as a point of care test for rapid diagnosis.

Authors and Affiliations

Krishnarao Arthi, S Geetha Banu

Keywords

Related Articles

Carcinosarcoma of Breast with Hormone Receptor and Her2/neu Positivity

Carcinosarcoma is an extremely rare tumor of the breast comprising of two distinct cell lines i.e. the epithelial and mesenchymal. It is a highly aggressive tumor with a poor prognosis compared to other breast cancers wi...

Prognostic Significance of p53, Ki-67 and Bcl-2 in Leukoplakia and Squamous Cell Carcinoma of the Oral Cavity

Introduction: Oral Squamous Cell Carcinoma (OSCC) is characterized by diversity in their biological behaviour which in turn forms the basis of deciding management options. It usually arises from Premalignant/Potentially...

Hemophagocytic Lymphohistiocytosis in Adults and Adolescents - Experience from a Tertiary Care Centre in South India

Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome of immune dysregulation. It is characterized by hypercytokinemia and macrophage activation resulting in fever, cytopenia, splenomegaly and hyperfe...

Solitary Nevus Lipomatosus Cutaneous Superficialis: A Case Report

Nevus Lipomatosus Cutaneous Superficialis (NLCS) is a rare benign hamartomatous skin tumor. It consists of infiltration of mature adipose tissue into the dermal collagen. It’s clinically classified in two types: the clas...

Download PDF file
  • EP ID EP610016
  • DOI 10.7860/NJLM/2019/39955:2332
  • Views 119
  • Downloads 0

How To Cite

Krishnarao Arthi, S Geetha Banu (2019). Prevalence of Group A Streptococcal Carriage Rate in Asymptomatic Children. National Journal of Laboratory Medicine, 8(2), 1-3. https://europub.co.uk./articles/-A-610016