Prevalence of H. Pylori Infection in the Histopathological Spectrum of Gastric Lesions in Endoscopic Gastric Biopsies
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Background: Upper gastrointestinal disorders are commonly seen in routine clinical practice. Most common gastric problems include acute and chronic gastritis, peptic ulcer, benign and malignant tumours. The endoscopic examination of upper GI is not only important in diagnosing common upper GI disorders, but also in evaluating these disorders by studying histopathology of endoscopic gastric biopsies. Role of H. pylori has been established in various gastric lesions. Materials and Methods: This is a prospective study done over a period of 4 years from January 2013 to December 2016 in Department of Pathology, Gian Sagar Medical College and Hospital, Banur. This study includes 80 patients who presented to Medicine out-patient department, with various gastric complaints and on whom endoscopic gastric biopsy was done. Tissue slides were stained with routine Hematoxylin & Eosin stain and Giemsa stain for H.Pylori. The spectrum of various gastric lesions were noted. Results: In Our study, chronic gastritis was found to be the most common lesion (89%) followed by gastric ulcer (7.5%), gastric polyp and adenocarcinoma (3.75% each) and MALToma (1.25%). Prevalence of H. Pylori is 53.75% in all lesions. H.pylori positivity was seen in 92% biopsies of chronic gastritis with activity, 26.7% positivity in chronic gastritis without activity, 25% of acute gastritis, 60% patients of chronic gastritis with intestinal metaplasia and all 06 patients (100%) of gastric ulcer. Gastric polyp and gastric adenocarcinoma showed 33.3% positivity. However, no H. Pylori was seen in MALToma and in normal biopsies. Conclusion: The present study revealed substantial prevalence of H. pylori positive patients in patients presenting to a tertiary care Hospital with a higher preponderance in males. Detection of H. Pylori in any population and its eradication in such patients may help in significant reduction in usage of acid suppression and morbidity resulting from H. Pylori related gastric lesions.
Authors and Affiliations
Monika Bansal, Anureet Kaur, Rimpi Bansal
Keywords
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- EP ID EP547562
- DOI 10.21276/ijmrp.2017.3.5.036
- Views 72
- Downloads 0
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