Prevalence of Helicobacter pylori infection in gastric and duodenal lesions as diagnosed by endoscopic biopsy
Journal Title: International Journal of Medical Science and Public Health - Year 2016, Vol 5, Issue 1
Abstract
Background: Helicobacter pylori is associated with various diseases, mainly, many benign, premalignant, and malignant lesions of the digestive system. Colonization of stomach by H. pylori and chronic active gastritis present a cause-and-effect relationship. Endoscopic biopsy allows the detection of H. pylori , which determines the treatment for peptic ulcer disease. Objective: To study the various spectrums of pathological lesions in patients with dyspepsia and the incidence of H. pylori in various pathological lesions. Materials and Methods: Seventy consecutive endoscopic gastric biopsies, which were received from patients present - ing with symptoms of dyspepsia, were included in the study. Routine hematoxylin and eosin stain and Giemsa-stained sections were examined for the histomorphological parameters associated with H. pylori infection and correlated with the incidence of H. pylori infection in each case. Result: Of the 70 cases, 40 cases (57.5%) were positive for H. pylori , maximum positivity (66.6%) in specimens with histological evidence of gastric ulcer, followed by positivity in chronic superficial gastritis with activity cases (61.5%). Adenocarcinoma of intestinal type was associated with more positivity [4 of 5 (80%)] cases than that of adenocarcinoma of diffuse type [1 of 4 (25%)] cases. The presence of H. pylori is directly proportional to the degree of inflammation in chronic superficial gastritis. Conclusion: The frequency of H. pylori infection is common in dyspeptic patients in our population. Association between various gastric diseases such as benign, premalignant, and malignant and H. pylori is significant.
Authors and Affiliations
Hiral Shah, Pinal Shah, Mayur Jarag, Rhuta Shah, Pinkal Shah, Kinnari Naik
Keywords
Related Articles
- EP ID EP128094
- DOI 10.5455/ijmsph.2016.1305201517
- Views 68
- Downloads 0
Prevalence and risk factors of isolated systolic hypertension among the elderly population in Davangere, Karnataka
Background: The WHO has estimated that globally hypertension is directly responsible for about 62% of cerebrovascular disease and 49% of ischemic heart disease. The risks of stroke and coronary heart disease are directly...
Sociodemographic profile and health status of children living with HIV–AIDS attached to an NGO (ADHAR) of Ahmedabad city
Background: Acquired immunodeficiency syndrome (AIDS) has emerged as one of the most serious public health problems in India. Objectives: This study was conducted (1) to study the sociodemographic profile of child...
Comparative evaluation of different doses of intravenous dexmedetomidine during laparoscopic cholecystectomy under general anesthesia
Background: Laparoscopy induces hemodynamic changes that lead to increased systemic vascular resistance, mean arterial pressure, heart rate, reduction in stroke volume, and cardiac output. Dexmedetomidine is a highly sel...
Relation between high sensitivity C reactive protein to obesity among indians
Background: Indians tend to have excess body fat and abdominal and truncal adiposity. These features have been referred to as the “Asian Indian phenotype or paradox.” The adipose tissue produces proinflammatory cytok...
Prevalance and fetomaternal outcome of thyroid disorder in pregnanacy
Background: Thyroid diseases are the commonest endocrine disorders affecting women of reproductive age group and hence constitute the commonest endocrine disorder in pregnancy also. It has long been recognized tha...